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S Apr 23 at 0:22 history edited David CC BY-SA 4.0
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Dec 21, 2016 at 3:19 comment added JayCkat I don't think the problem is torque. mainly because at the DNA level, water is very viscous. And DNA of a chromosomes being a very long molecule (tens centimeters long), a linear molecule would behave like a circular one, removing torque would be very difficult. My guess, is that organism with linear chromosome tend to be ones which under go meiosis. Chromosomes pairup, form chiasmata and exchange chromosome segments. On a linear chromosome, both odd and even exchange events resolve fine. In circular chromosomes, odd exchange lead to chromosome fusion. Even chiasmata resolve to two chromosomes
Dec 14, 2016 at 14:47 vote accept Artem Kaznatcheev
Mar 16, 2014 at 3:16 answer added Inesophet timeline score: 0
Apr 18, 2013 at 0:48 history edited Artem Kaznatcheev CC BY-SA 3.0
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Sep 8, 2012 at 0:02 history tweeted twitter.com/#!/StackBiology/status/244224159134146560
Sep 7, 2012 at 7:48 answer added R Stephan timeline score: 12
Sep 7, 2012 at 6:08 comment added bobthejoe Linking number? I think this goes with @MCM's torque issue.
Sep 7, 2012 at 3:48 comment added Artem Kaznatcheev @MCM if you could work that into an answer, I think it would be a decent one and I would enjoy reading it in detail. I was hopping for a more subtle answers (maybe related to life-histories), but I am happy with this, too :D.
Sep 7, 2012 at 2:51 comment added Artem Kaznatcheev @MCM that was my first guess, too... especially with the other big difference between pro and euk being the tight space of nucleus. However, I couldn't think of why folding a very long circular genome would be fundamentally more difficult than a linear one (in fact it would make certain kinds of knots more difficult, avoiding potential damage). I also know a negative amount of biology so couldn't think of how to start the literature search myself :D.
Sep 7, 2012 at 1:54 history edited Artem Kaznatcheev
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Sep 7, 2012 at 1:23 history asked Artem Kaznatcheev CC BY-SA 3.0