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About 2/3 of the antibiotics are used in animals.

https://youtu.be/iLJAleLjJv8?t=3m47s

We found 138 unique vendors selling antibiotics without a prescription. Of those vendors, 36.2% sold antibiotics without a prescription, and 63.8% provided an online prescription. Penicillins were available on 94.2% of the sites, macrolides on 96.4%, fluoroquinolones on 61.6%, and cephalosporins on 56.5%. Nearly all, 98.6%, ship to the United States.

http://www.bbc.com/news/health-34857015

Self-medication is more common in developing countries due to factors such as ready availability of antibiotics without prescription, the unrestricted access to antibiotics,lack of regulation over drugs, and physicians and pharmacists prescribing and dispensing antibiotics without regard to the cause of infection

http://article.sapub.org/10.5923.j.cmd.20110101.02.html#Sec3.3.4

We found 138 unique vendors selling antibiotics without a prescription. Of those vendors, 36.2% sold antibiotics without a prescription, and 63.8% provided an online prescription. Penicillins were available on 94.2% of the sites, macrolides on 96.4%, fluoroquinolones on 61.6%, and cephalosporins on 56.5%. Nearly all, 98.6%, ship to the United States.

http://www.bbc.com/news/health-34857015

Nutritive and therapeutic treatment of farm animals with antibiotics, amounting to half of the world's antibiotic output, has selected for resistant bacteria that may contaminate the food produced. Antibiotic-resistant enterococci and staphylococci from animals are found in food when they survive the production processes, as in raw cured sausages and raw milk cheeses1. The broad host ranges of some plasmids and the action of transposons in many bacteria allow antibiotic-resistance genes to be communicated by conjugation between different species and genera2,3. A multi-antibiotic resistance plasmid from a lactococcus found in cheese provides a historical record of such events.

http://www.nature.com/nature/journal/v389/n6653/abs/389801b0.html

• Pharmaceutical industry does not have enough interest in the antibiotics research, since it is not as profitable as for example cholesterol reducers. Antibiotics are cheap, and you usually heal after the first treatment, while the research and the clinical trials are really expensive, it is hard to find working chemicals, which do not have severe side effects.

• People with Mycobacter infections does not always do the treatment long enough, so Mycobacters can become resistant to antibiotics.

• There is no global regulation of how to use antibiotics, so in some countries you can buy them without consulting a doctor. This leads to overuse of antibiotics, and overusage leads to resistance.

• Some of the antibiocstics are used by agriculture industry, which leads to antibiotics resistance as well.

• Pharmaceutical industry does not have enough interest in the antibiotics research, since it is not as profitable as for example cholesterol reducers. Antibiotics are cheap, and you usually heal after the first treatment, while the research and the clinical trials are really expensive, it is hard to find working chemicals, which do not have severe side effects.

“We need to shift from the concept of the pharmacy as a ‘shop’ and build a culture of pharmaceutical services. This is already happening in some countries, but we need to make it the rule everywhere,” says Zsuzsanna Jakab, WHO Reg ional Director for Europe. “As pharmacists dispense medicines to patients,they are important allies in our fight against antibiotic resistance. As such, they need to be ena bled to deliver accurate information and counselling on proper antibiotic use.”

Over 40% of antibiotic prescriptions are inappropri ate, recent studies found. This relates especiallyto antibiotics prescribed for the common cold and sore throat; these most oftenresult from viral infections,on which antibiotics have no effect. Further, in some countries, there is atendency towards self-medication. Inappropriate an tibiotic use is the major driver of growing antibiotic resistance.

Pharmacists have decisive role in combating antibiotic resistance, says new WHO European survey

• People with Mycobacter infections does not always do the treatment long enough, so Mycobacters can become resistant to antibiotics.

• There is no global regulation of how to use antibiotics, so in some countries you can buy them without consulting a doctor and get a prescription. On top of this you can buy antibiotics without prescription on the internet if you want. This leads to overuse of antibiotics, and overusage leads to resistance.

We found 138 unique vendors selling antibiotics without a prescription. Of those vendors, 36.2% sold antibiotics without a prescription, and 63.8% provided an online prescription. Penicillins were available on 94.2% of the sites, macrolides on 96.4%, fluoroquinolones on 61.6%, and cephalosporins on 56.5%. Nearly all, 98.6%, ship to the United States.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746509/

These results demonstrate that, although illegal, the sale of antibiotics without a prescription continues in Spain.

http://cid.oxfordjournals.org/content/48/10/1345.full

• Some of the antibiocstics are used by agriculture industry, which leads to antibiotics resistance as well.