Timeline for Why is aneuploidy usually lethal?
Current License: CC BY-SA 3.0
6 events
| when toggle format | what | by | license | comment | |
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| Nov 7, 2016 at 5:48 | comment | added | GrumpyMammoth | @Roland Forgive me, my response was written past midnight. I meant to say that rather than progressing to the stage of dying from protein imbalance, the cell terminates before this point, usually. | |
| Nov 6, 2016 at 15:25 | comment | added | Roland | This sounds self-contradictory: you're saying that extra chromosomes are not harmful in themselves, but the cell detects them and self-terminates because extra chromosomes would be ... harmful? I'm no expert on this topic, but I would guess the main underlying problem is that aneuploidy causes problems in cell cycle/mitosis, which is lethal. Also, it probably would result in even more scrambled cells in the next generation (after meiosis), and so would endanger the whole genetic material. | |
| Nov 6, 2016 at 14:52 | comment | added | hesk | Just one doubt, but people with aneuploidy have problems because their aneuploidy translates into some sort of protein imbalance, and that brings me back to my question | |
| Nov 6, 2016 at 14:50 | vote | accept | hesk | ||
| Nov 6, 2016 at 14:50 | comment | added | hesk | Thanks for your reply, can you add something more about the "self error checking" mechanism, maybe a link?. | |
| Nov 6, 2016 at 1:52 | history | answered | GrumpyMammoth | CC BY-SA 3.0 |