Timeline for How is NAD+ used in lactic acid fermentation after it is oxidized from NADH?
Current License: CC BY-SA 4.0
11 events
| when toggle format | what | by | license | comment | |
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| Dec 19, 2022 at 18:46 | history | edited | David | CC BY-SA 4.0 |
Removed dead link
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| Oct 20, 2017 at 20:18 | vote | accept | Singh | ||
| Dec 13, 2016 at 17:49 | comment | added | David | @JagmeetSingh — Note that under aerobic conditions in the liver there are at least two other pathways glucose may be metabolized by other than glycolysis. Also it is precisely 2 net ATP in anaerobic glycolysis — the ones generated through the capture of phosphate in the GAPDH reaction. | |
| Dec 13, 2016 at 17:38 | comment | added | Singh | Actually, I saved you some headache. antranik.org/… This website it explained it well. | |
| Dec 13, 2016 at 17:29 | comment | added | Singh | I meant "decarboxylation" above and not "carboxylation". | |
| Dec 13, 2016 at 17:12 | comment | added | Singh | So just to clarify: Glucose gets converted to pyruvate and in absence of O2, it goes through fermentation BECAUSE it produces at least 2 ATP(?), and when there is O2 available, it proceeds to carboxylation of pyruvate --> Citric acid cycle and so on. My only confusion now is that why does glycolysis need to occur (anaerobically) if it can not even proceed to cellular respiration. | |
| Dec 13, 2016 at 12:04 | history | edited | David | CC BY-SA 3.0 |
italicized et al.
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| Dec 13, 2016 at 12:03 | comment | added | David | @JagmeetSingh — Happy to be of help. I've added a small section with a diagram indicating what happens to the NADH under aerobic conditions. The various possible fates of pyruvate (and glucose 6-phosphate) belong in an answer to a different question. If you have not yet met oxidative phosphorylation and the TCA cycle, then you will need to take your time learning about them — very important, but lots of detai. | |
| Dec 13, 2016 at 11:58 | history | edited | David | CC BY-SA 3.0 |
Added material on aerobic glycolysis
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| Dec 13, 2016 at 0:49 | comment | added | Singh | You understood exactly what my question was even when I myself was confused about what my question exactly is. Thank you so much. Your diagram helped. Now, I understand your diagram and why different steps are needed, but can you please help me understand the bigger picture. So the cycle in your diagram occurs when there is a lack of oxygen, i.e while exercising. But what happens where O2 is present (when we are not exercising) then there shouldn't be any lactate (b/c we dont get sore when we are sitting), if there is no lactate, means NADH doesnt get converted to NAD? | |
| Dec 12, 2016 at 14:11 | history | answered | David | CC BY-SA 3.0 |