Timeline for Translation of RNA into proteins
Current License: CC BY-SA 3.0
22 events
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| Apr 14, 2017 at 15:05 | history | tweeted | twitter.com/StackBiology/status/852900740611932160 | ||
| Mar 30, 2017 at 18:57 | comment | added | AliceD♦ | @David - I know the rules and you are right. The thing is that it is a gray area. Personally, I indeed never give answers-disguised-as-comments, only when I expect the question to be closed and close-voting myself. Anyway, point taken. | |
| Mar 30, 2017 at 18:52 | comment | added | Artem | Yes we can imagine that a tRNA can be recycled to incorporate the same amino acid into the same peptide chain multiple times so 16 tRNA could form a 50 amino acid chain but that will never happen thermodynamically. You need large concentrations of tRNA of all kinds for this reaction to take place, if you mix a single ribosome, mRNA and 15 tRNA with abundant free amino acids the reaction chemistry won't function. | |
| Mar 30, 2017 at 17:13 | answer | added | David | timeline score: 2 | |
| Mar 30, 2017 at 16:53 | comment | added | David | Jasmin — OK, but a strange question. And there are 20 different amino acids encoded in the standard genetic code, so I don't know why you picked 15, although a 50 amino acid protein could conceivably be lacking five amino acids. I suppose I have to answer your question now though. | |
| Mar 30, 2017 at 15:53 | comment | added | Jasmin Badawy | @David I hope that my question is clearer now. (Sorry for the inconvenience, but English is not my first language) | |
| Mar 30, 2017 at 15:51 | history | edited | Jasmin Badawy | CC BY-SA 3.0 |
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| Mar 30, 2017 at 15:31 | comment | added | David | Jasmin — Of course. But it was not obvious to me that this is what your question was about. Assuming that this is not a homework question (is it?) you need to explain very clearly what your question is. 1. When you say "particular tRNA molecule" do you mean the same identical one molecule in the cell or molecules of the same class, i.e. with the same anticodon. 2. When you say "two similar amino acids" you need to make it clear that you are refering to two alanines or two glycines (I would use identical, rather than similar). Your question is still unclear, which is why it has close votes. | |
| Mar 30, 2017 at 15:11 | comment | added | Jasmin Badawy | @David Can't there be two amino acids of the same codon be found in one polypeptide chain of protein, as alanine to be present more than one time in the chain?! | |
| Mar 30, 2017 at 15:07 | comment | added | canadianer | The only thing that comes to mind would be an error in tRNA charging. | |
| Mar 30, 2017 at 14:52 | comment | added | David | @AliceD — I didn't make the rules, but I subscribed to them when I signed on. I also understand them. They are clearly explained on biology.stackexchange.com/tour. When the people who have set this site up feel so strongly about this rule that they put a reminder in the comment box, there is really no justification for flouting it. If one person does it others think it is permissible and one ends up with the sort of discussion forum and chit-chat that StackExchange expressly is not. If people are uncomfortable with the rules they should go somewhere else. | |
| Mar 30, 2017 at 14:45 | comment | added | David | Jasmin, each codon (not code) specifies only one amino acid (in a given organism and subcellular compartment). GCG is the codon for alanine. If you think a codon can specify more than one amino acid (except in the special cases of selenocysteine) then you should study an elementary text on the genetic code. | |
| Mar 30, 2017 at 13:12 | comment | added | AliceD♦ | @David - it often happens that users do not feel confident writing up a full answer and comment. In my opinion, that is not breaking the model but making helpful comments to the user that won't do as a full blown answer. See e.g. meta | |
| Mar 30, 2017 at 13:09 | comment | added | Jasmin Badawy | @David amino acid having the same code ex: two amino acid molecules with (GCG) code. | |
| Mar 30, 2017 at 13:08 | review | Close votes | |||
| Apr 3, 2017 at 21:47 | |||||
| Mar 30, 2017 at 13:03 | comment | added | David | Please clarify what you mean by "of the same type". | |
| Mar 30, 2017 at 13:01 | comment | added | David | @YordanYordanov — "Use comments to ask for more information or suggest improvements Avoid answering questions in comments." You see these instructions when you click in a comment box. Please follow them or you are breaking the SE model. | |
| Mar 30, 2017 at 12:58 | comment | added | Yordan Yordanov | I have to check this out but aren't the amino acids modified after they become inserted into the growing chain, not before. I will make a quick search online now. Here is one paper I managed to find with a very "quick" online search-ncbi.nlm.nih.gov/pmc/articles/PMC3130931 . As far as I can see all modifications are done after translation, not before. But there might be exceptions yet. I guess I would have to go deeper for this question. | |
| Mar 30, 2017 at 12:53 | history | edited | Jasmin Badawy | CC BY-SA 3.0 |
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| Mar 30, 2017 at 12:50 | comment | added | AliceD♦ | @YordanYordanov although physiologically I agree, and it answers the question, I just am wondering: there must undoubtedly be chemically modified amino acids variants that will be inserted into the growing peptide as well right? | |
| Mar 30, 2017 at 12:39 | comment | added | Yordan Yordanov | No, there is no way the same species of tRNA can carry two different amino acids no matter how similar they are. Each tRNA carries only one particular species of amino acid and there is no way it can just "switch to" any other one. | |
| Mar 30, 2017 at 12:30 | history | asked | Jasmin Badawy | CC BY-SA 3.0 |