Timeline for Is it possible to separate either father or mother chromosomes from a sperm?
Current License: CC BY-SA 4.0
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S Dec 14, 2022 at 8:52 | history | suggested | tripleee | CC BY-SA 4.0 |
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S Dec 14, 2022 at 8:52 | |||||
Jul 23, 2017 at 0:00 | comment | added | Remi.b | I will answer one more time then :) Assuming that by mother and father you are referring to the parents of the male who produced the sperm (but you still have not explained what you actually meant by mother and father), then the answer is 'no' 1) because, obviously, flow cytometry is not able to brake and recombine chromosomes to undo what recombination just did and 2) the only potential markers of whether a chromosome comes from the 'mother' or the 'father' is a few epigenetic differences that can't be detected via flow cytometry. I'm out repeating that now! Good luck Daniel! | |
Jul 22, 2017 at 23:47 | comment | added | Daniel | Sorry you seem confused,I will ask one more time Can sperm sorting empty either all the father or mothers genes from a sample of sperm? | |
Jul 22, 2017 at 23:43 | comment | added | Remi.b | You are repeating the same question over and over but I still don't get it! Try to write more than a one line question. Give some context and maybe I will be able to understand what you're trying to ask. I think your question makes no sense (but might be wrong) but I can't tell what is your misunderstanding as long as you limit your phrasing to a single one liner question. | |
Jul 22, 2017 at 23:42 | comment | added | Remi.b | I am not sure what you call mother and father. I suppose it is what I call grandfather and grandmother, right? The answer (but I am not sure I understand what you're asking) is 'no' because it makes no sense due to recombination. Even if there was no recombination, you could not because the only eventual difference between maternally inherited and paternally inherited chromosomes are epigenetic modifications (which flow cytometry won't help you to distinguish). | |
Jul 22, 2017 at 23:35 | comment | added | Daniel | if we use flow cytometry can seperate the autosomes and the sex chromosomes of the father or mother from the sperm? | |
Jul 22, 2017 at 23:32 | comment | added | Remi.b |
The expression chromosomes genes is unclear and suggest that you don't really understand what a gene. I am still a bit unsure of what you are asking but you can't tell what chromosome come from which grandparent (whether in a sperm cell, in an ovule or in a zygote), the main reason being that recombination shuffled them up together.
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Jul 22, 2017 at 23:29 | comment | added | Daniel | I asking is it possible to empty all the chromosomes genes from the father or mother from the sperm to have either father or mother chromosomes? | |
Jul 22, 2017 at 23:24 | comment | added | Remi.b | I don't understand.... Do you mean whether we can separate sperms carrying the grandmother haplotype or the grandfather haplotype? Note that segregation and recombination make that gametes carry some mixture of the two grandparents haplotypes. (Here by grandparent, I refer to the parents of the male producing the sperm). Btw, is there any reason you talk about sperms and not ovules? | |
Jul 22, 2017 at 23:17 | comment | added | Daniel | I mean the autosomes from the father or mother chromosomes | |
Jul 22, 2017 at 22:24 | comment | added | Daniel | I'm actually asking can we seperate those xy or xx chromosome that carry genes? | |
Jul 22, 2017 at 20:48 | history | edited | Remi.b | CC BY-SA 3.0 |
added 50 characters in body
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Jul 22, 2017 at 20:33 | history | answered | Remi.b | CC BY-SA 3.0 |