Timeline for What is the definition of an opioid, beyond that it's something that stimulates opioid receptors?
Current License: CC BY-SA 3.0
7 events
| when toggle format | what | by | license | comment | |
|---|---|---|---|---|---|
| Aug 14, 2017 at 3:48 | vote | accept | uhoh | ||
| Aug 11, 2017 at 18:31 | comment | added | Alan Boyd | The introduction to this paper – Involvement of Endogenous Enkephalins and β-Endorphin in Feeding and Diet-Induced Obesity – refers to opioid peptides as: endogenous opioids (twice); endogenous opioid peptides; endogenous ligands of opioid receptors; endogenous opioid activity; and finally states that 'This study aimed to distinguish the role of the two major classes of endogenous opioids acting at MORs and DORs, namely enkephalins and β-endorphin...'. | |
| Aug 11, 2017 at 15:24 | comment | added | anongoodnurse | Perhaps, but a Google Scholar search of 2016-2017 Neuropharmacology papers on opioids fails to refer to any endogenous opioid peptides as "opioids". | |
| Aug 11, 2017 at 15:05 | comment | added | Alan Boyd | ...I think the use of the term 'opioid peptide' is just a way of emphasising what is being discussed in a specific context. | |
| Aug 11, 2017 at 15:05 | comment | added | Alan Boyd | @anongoodnurse Ref 2 of the WP page for opioids is as follows: Hemmings et al. (2013). Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application: Expert Consult - Online and Print. Elsevier Health Sciences. p. 253. ISBN 1437716792. "Opiate is the older term classically used in pharmacology to mean a drug derived from opium. Opioid, a more modern term, is used to designate all substances, both natural and synthetic, that bind to opioid receptors (including antagonists)." [my emphasis] ... | |
| Aug 11, 2017 at 14:16 | comment | added | anongoodnurse | The only issue I have with this answer is that endorphins, enkephalins, etc. are not listed as opioids but as "opioid peptides" (most commonly), "opioid neuropeptides", or opiate-like pentapeptides or some such, as far back as 1977. So far, I have not seen them referred to as opioids. | |
| Aug 11, 2017 at 13:51 | history | answered | Alan Boyd | CC BY-SA 3.0 |