Timeline for Why aren't drugs delivered directly into arteries, rather than veins?

Current License: CC BY-SA 3.0

8 events

when toggle format	what		by	license	comment
May 3, 2018 at 1:59	answer	added	bjarchi		timeline score: 0
Aug 16, 2017 at 22:52	history	edited	Bryan Krause♦	CC BY-SA 3.0	edited title
Aug 16, 2017 at 22:45	review	Close votes
Aug 21, 2017 at 14:43
Aug 16, 2017 at 21:00	answer	added	Bryan Krause♦		timeline score: 3
Aug 16, 2017 at 19:15	comment	added	Bryan Krause♦		Further, most IV drugs are given through easily accessed veins such as in the arm: these return to the heart before any pass through the liver or spleen. Unless you were trying to deliver the drug to the arterial circulation of that particular hand, it's going to circulate before it gets to the target organs. And if your drug is going to damage the liver, why don't you think it's going to be dangerous for anything else? The liver isn't particularly vulnerable, quite the opposite.
Aug 16, 2017 at 19:10	comment	added	anongoodnurse		Seriously, the aorta? It's not accessible, and you don't want to mess with it. Veins are used because they are low pressure and low risk. You can't administer a drip into a high pressure artery; the blood would back up into the tubing; in fact, there is enough pressure in just the radial artery to push a plunger up as it fills the syringe. Also, it would keep bleeding as long as there was a needle or tube in it. Damaging a vein is no big deal, damaging an artery is. Finally, regarding metabolism, just give enough drug to minimize the effect of first pass metabolism.
Aug 16, 2017 at 19:10	comment	added	Chris♦		Because of the risks of putting a needle in an artery. Additionally: After a few heart strokes the drug is distributed in the blood and it is going through the liver anyway, most drugs are processed there.
Aug 16, 2017 at 18:59	history	asked	Imprisoned Rhesus	CC BY-SA 3.0