Timeline for Number and function of voltage-independent ion channels
Current License: CC BY-SA 3.0
15 events
| when toggle format | what | by | license | comment | |
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| Sep 18, 2017 at 12:46 | history | edited | vkehayas | CC BY-SA 3.0 |
small fix
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| Sep 15, 2017 at 14:47 | vote | accept | Hans-Peter Stricker | ||
| Sep 13, 2017 at 15:38 | comment | added | Hans-Peter Stricker | @Bryan: 1) goes too deeply into details, 2) is more concerned with what we know than how things are. | |
| Sep 13, 2017 at 15:37 | comment | added | Hans-Peter Stricker | @vkehayas: I found Bryan's suggestion of NEURON (in his last comment on his answer here: biology.stackexchange.com/a/65641/27928) | |
| Sep 13, 2017 at 14:20 | comment | added | Hans-Peter Stricker | Might turn out to be the same. | |
| Sep 12, 2017 at 18:29 | comment | added | vkehayas | Without knowing to what exactly you are referring to, I'd venture to say that they are talking about inter-channel distances, i.e. distances from/to every ion channel's closest neighbour. | |
| Sep 12, 2017 at 17:04 | comment | added | Bryan Krause♦ | Nice answer, I have two add-ons: 1) a lot of ion channels, regardless of gating, are made up of multiple subunits. In some cases they are not only heteromultimers, but each protein component can have multiple varieties that can each fit in with the other subunits. Because those subunits are somewhat exchangeable, the number of unique ion channels is quite high, although not all combinations are often observed for various reasons. 2) Lots of channels that are not thought of as voltage-gated still show some voltage dependancy. For example, IRK channels. | |
| Sep 12, 2017 at 16:09 | comment | added | Hans-Peter Stricker | Marginal note: I said "mainly concerned", not "solely concerned". | |
| Sep 12, 2017 at 16:06 | comment | added | Hans-Peter Stricker | First thing I stumbled upon at channelpedia: What does "distributed exponentially" mean? With respect to which variable (distance from soma?), and with positive or negative exponent? (I would guess negative, because channels decrease resistance, thus increase the time constant, thus decrease speed of propagation). | |
| Sep 12, 2017 at 15:51 | comment | added | Hans-Peter Stricker | Thanks anyway for your answer, I'll try to follow your advice(s). | |
| Sep 12, 2017 at 15:50 | comment | added | Hans-Peter Stricker | Oops, I seem to have overseen something (what a shame): when did Bryan suggest NEURON to me? | |
| Sep 12, 2017 at 14:35 | history | edited | vkehayas | CC BY-SA 3.0 |
expanded answer to second question
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| Sep 12, 2017 at 13:58 | history | edited | vkehayas | CC BY-SA 3.0 |
clarified post-script
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| Sep 12, 2017 at 13:48 | history | edited | vkehayas | CC BY-SA 3.0 |
responded to the second question
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| Sep 12, 2017 at 13:39 | history | answered | vkehayas | CC BY-SA 3.0 |