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Nov 12, 2017 at 15:28 history bumped CommunityBot This question has answers that may be good or bad; the system has marked it active so that they can be reviewed.
Oct 13, 2017 at 14:57 history edited AliceD
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Oct 13, 2017 at 14:57 answer added AliceD timeline score: 1
Oct 13, 2017 at 10:34 comment added Hans-Peter Stricker Let us continue this discussion in chat.
Oct 13, 2017 at 10:29 comment added vkehayas My comments are here to help you revise your question, so please refrain from starting a conversation in the comments unless something I said is not clear. Your last three comments could be incorporated in the question, IMHO.
Oct 13, 2017 at 10:29 comment added vkehayas That may happen to some extent (that's why I said mostly), but it's highly unlikely, based on first principles: if it was extensive at all, it would prevent neural migration. Don't confuse "pioneer neurons" and their axons with how you used the term, as they project after they have arrived at their target area.
Oct 13, 2017 at 10:12 comment added Hans-Peter Stricker For example, it might be the case that some "pioneer" axons connect rather early to their target neuron, then follow it (during its travel) by lengthening, and thus help somehow to guide the following axons (somehow like the emigrant trails led by pioneers in North America in the 19th century), which connect to their targets only later.
Oct 13, 2017 at 9:50 comment added Hans-Peter Stricker I cannot believe that all neurons have to be at their final positions before synaptogenesis starts. It must be (in my humble opinion), that at least some neurons already connect during their travel to their final positions, so there must also be axon growth just by lengthening, not only guided. But of course I may be wrong.
Oct 13, 2017 at 9:21 comment added Hans-Peter Stricker The Wikipedia article describes Case 2. But does it explicitly rule out Case 1?
Oct 13, 2017 at 9:20 comment added Hans-Peter Stricker What do the commissural fibers connect? (See biology.stackexchange.com/questions/65351/…)
Oct 13, 2017 at 9:09 comment added vkehayas Not an expert on this but Case 1 is mostly wrong. Have you read this: en.wikipedia.org/wiki/Axon_guidance. Also, interhemispheric connections are rather rare, at least in the cortex.
Oct 13, 2017 at 8:46 history asked Hans-Peter Stricker CC BY-SA 3.0