Timeline for What would be the fate of protein made from D-amino acids after ingestion by humans?
Current License: CC BY-SA 4.0
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| Jul 28, 2023 at 16:20 | comment | added | David | @totalMongot I think you misinterpret what the poster wrote — certainly the state of chemical synthesis of peptides from amino acids. This was first achieved at the beginning of the 20th century, led to the synthesis of peptide hormones by the 1950s, and was made much more efficient by the introduction of the solid support methodology for which Merrifield received the Nobel prize in 1984. My mailbox is full of offers from companies that do this. Naturally L-amino acids were used, but D-amino acids will react similarly. That’s the point of needing to explain enzyme specificity towards L. | |
| Jul 27, 2023 at 10:16 | comment | added | totalMongot | Yes that's not the question, but I asked because the OP said that in his question: "There are some natural peptides made of D-amino acids, rather than the L-amino acids normally found in nature. It is now possible to chemically synthesize artificial proteins made of D-amino acids." | |
| Jul 27, 2023 at 9:45 | comment | added | David | @totalMongot — Of course they can, but that is not the question. | |
| Jul 25, 2023 at 19:38 | comment | added | totalMongot | Could you please add an explanation about why L-amino acid could not be used to artificially synthetize proteins? | |
| May 11, 2018 at 23:50 | vote | accept | nick012000 | ||
| May 10, 2018 at 16:19 | history | answered | David | CC BY-SA 4.0 |