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Timeline for Complete human rDNA sequence

Current License: CC BY-SA 4.0

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Jun 9, 2018 at 1:19 comment added JayCkat Welcome to the "gaps" in human genome. Parts of the genome of eukaryote that are very difficult to explore must less experiment with. Here is a reference but it does quite cover recombinational instability of repeat arrays that prevent other methods to study them. ncbi.nlm.nih.gov/pmc/articles/PMC5098217
Jun 8, 2018 at 19:05 comment added David Reference in support of this assertion please. I thought methodological developments in sequencing meant that this situation could be dealt with.
Jun 8, 2018 at 14:12 comment added JayCkat Yes, there must be sequence variability in the non-coding region. However as rDNA arrays are rather unstable and recombine within a yeast or ecoli host. Hence isolating rDNA repeat array and making a rough map of rDNA repeat arrays is next to impossible.
Jun 8, 2018 at 14:08 history edited JayCkat CC BY-SA 4.0
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Jun 8, 2018 at 10:31 comment added matk Great, that's useful to know. I assume that there must be mutations in at least some of the noncoding regions that would enable positional information for certain sequences.
Jun 8, 2018 at 9:33 history answered JayCkat CC BY-SA 4.0