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Jan 4, 2019 at 12:49 comment added RKK It is specific to the task. If homozygous is not lethal, then i would go for homozygous line, as it will be easy to maintain. In case if you maintain heterozygous, then screening at each generation is necessary.
Jan 3, 2019 at 22:23 comment added Maxmansung Thank you very much for the response. In general is it preferred to gain a homozygous or a hetrozygous change or is it specific to the intended task?
Jan 3, 2019 at 11:51 history answered RKK CC BY-SA 4.0