Timeline for Why can't bacteriophages survive inside the human body thus negating the possibility of using them against bacteria?
Current License: CC BY-SA 4.0
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Jan 23, 2019 at 10:35 | comment | added | Frieke | While most phages are no threat for human health, they are "biological agents" falling into the biosafety level 1 regulation. When they are modified in the lab, that level might even increase. So, your lab needs to meet all safety standards to be allowed to handle them. journals.sagepub.com/doi/pdf/10.1177/153567601001500106 | |
Jan 22, 2019 at 5:04 | comment | added | user1258361 | Are the special safety rules for bacteriophage treatment really needed or only a matter of paranoid bureaucratic overhead? Intuitively, bacteriophages should be the safest viruses for humans to be exposed to considering they selectively infect bacteria (fundamentally different biological architecture from human cells). For bacteriophages to infect humans, first they need to figure out infecting eukaryotes, and then they need to adapt to the different ribosome structure (which also happens to be the reason why you can take macrolide antibiotics without shutting down your own ribosomes). | |
Jan 10, 2019 at 15:23 | vote | accept | Amrita Mallick | ||
Jan 10, 2019 at 14:03 | history | answered | Frieke | CC BY-SA 4.0 |