Skip to main content
3 of 3
added 287 characters in body
nachocab
  • 175
  • 1
  • 2
  • 8

What is the difference between a phosphotransferase, a phosphatase, a phosphorylase and a kinase?

I've looked in several sources, but I'm still confused. This is what I have so far:

  • A phosphotransferase catalyzes the addition of a phosphate group.

  • A kinase is a type of phosphotransferase that transfers a phosphate group from ATP to a substrate.

  • A phosphorylase is a type of phosphotransferase that catalyzes the addition of a phosphate group from an inorganic phosphate (HPO4) to a substrate.

  • A hydrolase catalyzes the hydrolysis of a chemical bond.

  • A phosphatase is a type of hydrolase that removes a phosphate group.

Is this right?

EDIT: Also adding to the confusion is the enzyme Phosphorylase kinase, which is the kinase that phosphorylates the enzyme Glycogen phosphorylase, which hydrolyzes glycogen.

nachocab
  • 175
  • 1
  • 2
  • 8