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An antigen is a substance which causes the the body to produce a reaction of the adaptive immune system. Contact of the immune system to antigens results in the production of highly specific (antigen specific) antibodies.

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Minimum size for a peptide/protein to be immunogenic in human?

What is the minimum size for an (injected) peptide/protein to cause immunogenic response in human? A reference is very helpful, as well. Thanks in advance
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