Skip to main content
Biology

Return to Question

Bumped by Community user
Bumped by Community user
Simplified using standard scientific terminology
Source Link
David
David
  • 26.6k
  • 8
  • 53
  • 95

What do we use asis the baseline to determine what genetic segments are "mutations" (and what are not)in a genome

In order to determine whether a particular segment of the genome iscontains a mutation, it seems to me that there must first be a baseline code on whichreference sequence that code looks somehow differentis known to be unmutated.

How has the baselinewas such a human reference genome been determined? Did someone dig upIs it the DNA sequence of a very_old human skeleton which was subsequently DNA-analyzed to be used as the baseline?

  Or do mutations contain some kind of fingerprint that tells researchersindicates that "it“it is not the original genome"? If so, how does that fingerprint look likegenome”?

What do we use as baseline to determine what genetic segments are "mutations" (and what are not)

In order to determine whether a particular segment of the genome is a mutation, there must first be a baseline code on which that code looks somehow different.

How has the baseline genome been determined? Did someone dig up a very_old human skeleton which was subsequently DNA-analyzed to be used as the baseline?

  Or do mutations contain some kind of fingerprint that tells researchers that "it is not the original genome"? If so, how does that fingerprint look like?

What is the baseline to determine what are "mutations" in a genome

In order to determine whether a particular segment of the genome contains a mutation, it seems to me that there must first be a reference sequence that is known to be unmutated.

How was such a human reference genome determined? Is it the DNA sequence of a very_old human skeleton? Or do mutations contain some kind of fingerprint that indicates that “it is not the original genome”?

Bumped by Community user
Bumped by Community user
Bumped by Community user
Bumped by Community user
Bumped by Community user
The question confuses 'genetic code' with 'genome'. It is important to eliminate all such instances.
Source Link
edit approved Mar 23, 2016 at 1:46
David
edit approved Mar 23, 2016 at 1:46
David
  • 26.6k
  • 8
  • 53
  • 95

In order to determine whether a particular segment of genetic codethe genome is a mutation, there must first be a baseline code on which that code looks somehow different.

How has the baseline codegenome been determined? Did someone dig up a very_old human skeleton which was subsequently DNA-analyzed to be used as the baseline?

Or do mutations contain some kind of fingerprint that tells researchers that "it is not the original code"genome"? If so, how does that fingerprint look like?

In order to determine whether a particular segment of genetic code is a mutation, there must first be a baseline code on which that code looks somehow different.

How has the baseline code been determined? Did someone dig up a very_old human skeleton which was subsequently DNA-analyzed to be used as the baseline?

Or do mutations contain some kind of fingerprint that tells researchers that "it is not the original code"? If so, how does that fingerprint look like?

In order to determine whether a particular segment of the genome is a mutation, there must first be a baseline code on which that code looks somehow different.

How has the baseline genome been determined? Did someone dig up a very_old human skeleton which was subsequently DNA-analyzed to be used as the baseline?

Or do mutations contain some kind of fingerprint that tells researchers that "it is not the original genome"? If so, how does that fingerprint look like?

Source Link
user12939
user12939

What do we use as baseline to determine what genetic segments are "mutations" (and what are not)

In order to determine whether a particular segment of genetic code is a mutation, there must first be a baseline code on which that code looks somehow different.

How has the baseline code been determined? Did someone dig up a very_old human skeleton which was subsequently DNA-analyzed to be used as the baseline?

Or do mutations contain some kind of fingerprint that tells researchers that "it is not the original code"? If so, how does that fingerprint look like?