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A rapid change in the membrane potential of excitable cells such as neurons and muscles; this usually involves a steep rise (depolarization) followed by a steep fall in membrane potential (repolarization). The cell subsequently enters a short refractory period (hyperpolarized state) during which it cannot generate another action potential.

1 vote
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187 views

What is the derivation of the rules of proportionality between axon conduction velocity and ...

We have been told that in myelinated fibres, conduction velocity is proportional to the diameter of the axon. In unmyelinated fibres, velocity is proportional to the square root of the diameter. Can …
D.J. Lawson's user avatar
5 votes
1 answer
456 views

What is the mechanism by which myelination reduces the capacitance of the axon membrane?

There are two mechanisms that have been proposed to me. 1) Layering of Schwann cell membrane with conducting fluid between the layers is analogous to several capacitors in series. Since capacitance i …
D.J. Lawson's user avatar