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A rapid change in the membrane potential of excitable cells such as neurons and muscles; this usually involves a steep rise (depolarization) followed by a steep fall in membrane potential (repolarization). The cell subsequently enters a short refractory period (hyperpolarized state) during which it cannot generate another action potential.

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Original paper about the all or none law for neurons

This probably goes back to Lucas (1909), Adrian (1912), and Bernstein (1912). But the idea might have started from Helmholtz (1850). Lucas, K (1909). The ``all or none'' contraction of the amphibian …
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