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The branch of statistics that deals with data relating to living organisms.
4
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Why genes are assumed to follow multivariate normal?
I wonder why gene expression data are very frequently modeled by multivariate normal distributions. What is the reason for those strong assumptions that the genes follow multivariate gaussian? Are the …
0
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0
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Is it okay to scale the RNA-Seq counts after log-transformation?
On an RNA-Seq dataset, I want to apply a clustering algorithm which requires zero-mean uni-variance gene expression levels. I am wondering whether it makes sense to use "scale" function in R after tak …