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Chromatin is the complex of DNA, histones, and other scaffolding proteins that make up the chromosomes, which in eukaryotes is located in the nucleus of the cell.
3
votes
1
answer
70
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In chromatin, what are the differences among states, interactions, and structures?
I am new to the study of chromatin, and I am trying to understand what people mean when they write about chromatin states, chromatin interactions, and chromatin structures. …
4
votes
1
answer
582
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What are "anchor regions" in the human genome?
I've been reading this paper entitled "A high-resolution map of the three-dimensional chromatin interactome in human cells", about interactome in 3D chromatin. … anchor regions in
the human genome, with each containing one or a few HindIII
restriction fragments (fragments shorter than 2 kilobases (kb) are
merged) (Fig. 2a), and uncovered a total of 1,116,312 chromatin …
4
votes
1
answer
371
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Why is it important to study chromatin to understand cancer?
Chromatin states, chromatin interactions, chromatin loopings, chromatin behaviours, etc. seem to have become the new priority of cancer scientists. … These questions just flowed into my mind:
What is the relationship between chromatin and cancer?
In cancer research, why is it so important to study chromatin and how chromatin loopings form? …