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Chromatin is the complex of DNA, histones, and other scaffolding proteins that make up the chromosomes, which in eukaryotes is located in the nucleus of the cell.

3 votes
1 answer
70 views

In chromatin, what are the differences among states, interactions, and structures?

I am new to the study of chromatin, and I am trying to understand what people mean when they write about chromatin states, chromatin interactions, and chromatin structures. …
DavideChicco.it's user avatar
4 votes
1 answer
582 views

What are "anchor regions" in the human genome?

I've been reading this paper entitled "A high-resolution map of the three-dimensional chromatin interactome in human cells", about interactome in 3D chromatin. … anchor regions in the human genome, with each containing one or a few HindIII restriction fragments (fragments shorter than 2 kilobases (kb) are merged) (Fig. 2a), and uncovered a total of 1,116,312 chromatin
DavideChicco.it's user avatar
4 votes
1 answer
371 views

Why is it important to study chromatin to understand cancer?

Chromatin states, chromatin interactions, chromatin loopings, chromatin behaviours, etc. seem to have become the new priority of cancer scientists. … These questions just flowed into my mind: What is the relationship between chromatin and cancer? In cancer research, why is it so important to study chromatin and how chromatin loopings form? …
DavideChicco.it's user avatar