I am not a biologist, so please pardon the overly noob question. Some genes are TFtranscription factors (TF) and regulate other genes. My question is: if a gene is NOT a TF gene, can it regulate itself? E.g. given a system of 3 genes {g1,g2,g3}
where only g1
and g2
are TF, then in a gene regulatory network, what are ALL possible parental sets of g3
(where in this GRN, you put a directed edge from the regulating gene to the regulated gene)? Will it be {{g1},{g1,g2},{g2},{}}
or {{g3,g1},{g3,g1,g2},{g3,g2},{g3}}