I live in Northern Indiana and I’ve seen 3 of these spiders in my house before, all different ones. When I first saw it, it scared me since it’s a pretty big spider in my opinion from what I usually have seen around here. This spider was bigger than a quarter all together. I know it’s not the best picture, but this is it on the wall a while ago. Also was a very fast spider so I couldn’t capture it too well. Are they harmless? I woke up with a bite today and then I remembered this!
I'm also from Northern Indiana. There's only two spider species in the area that are venomous: the Brown Recluse and the Black Widow. It's hard to tell from the picture, but I'm fairly certain that its not a Recluse, and it's definitely not a Black Widow. My best guess would be a Barn Tunnel Weaver.
For future reference: https://spiderid.com/locations/united-states/indiana/ has a list species, with pictures.
https://www.in.gov/dnr/entomolo/4542.htm for more info on Brown Recluses and Black Widows.