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The science of collecting and analyzing complex biological data such as genetic codes using informatics.

1 vote
0 answers
77 views

Why Pan_troglodytes-2.1.3 Assembly renamed as a Pre in ENSEMBL?

I began working with panTro3 assembly of the UCSC. This assembly corresponds to CGSC Build 2.1.3. See here: https://genome.ucsc.edu/FAQ/FAQreleases.html Now, I have to cross annotations with ENSEMBL …
je_b's user avatar
  • 211
3 votes
2 answers
5k views

What is the meaning of dots and dashes in clustalw?

I am converting outputs in stockholm format to clustalw using Bio::AlignIO->new(-file => "$ARGV[0]", -format => "stockholm"); and Bio::AlignIO ->new (-format =>'clustalw'); I am also using my $ …
je_b's user avatar
  • 211
2 votes
1 answer
482 views

Stockholm format to dot-brackets format?

I need to convert all my sequences in a Stockholm format into this: hg19_11_6_Ala ----------------.GG--gggaguggugu....gguuacgaaugUGGCCUCUGC-----AA............................................ …
je_b's user avatar
  • 211
2 votes
2 answers
157 views

Core Biological concepts explained to a Computer Scientist?

I am a computer scientist delving into Bioinformatics and I need to gain insight in biological phenomena. …
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  • 211