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In molecular genetics, an open reading frame is the part of a reading frame that has the ability to be translated. An ORF is a continuous stretch of codons that may begin with a start codon and ends at a stop codon.

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How do biologists infer correct ORF of a DNA sequence?

Each DNA (RNA) sequence has 6 possible Open Reading Frames(ORF). My question is: What are the theoretical bases of in vitro or in silico tries to find correct reading frame of a sequence? …
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