Since bacteria can evolve to overcome antibiotic use, why wouldn't be able to evolve to overcome antibody or cell-mediated immunity?

Thanks

One possible explanation: antibiotics have only one target while vaccines elicit antibodies against multiple targets and multiple T-cell epitopes. Even more targets arise when comparing subunit vs inactivated vaccines, where the number of targets are extremely higher using inactivated vaccines, containing whole bacterial cell.

Since bacteria can evolve to overcome antibiotic use, why wouldn't they be able to evolve to overcome antibody or cell-mediated immunity?

(One possible explanation: antibiotics have only one target while vaccines elicit antibodies against multiple targets and multiple T-cell epitopes. Even more targets arise when comparing sub-unit vs inactivated vaccines, where the number of targets are extremely higher using inactivated vaccines, containing whole bacterial cell.)

Since bacteria can evolve to overcome antibiotic use, why wouldn't be able to evolve to overcome antibody or cell-mediated immunity?

One possible explanation is that antibiotics have only one target while vaccines elicit antibodies against multiple targets and multiple T-cell epitopes.

Thanks

Since bacteria can evolve to overcome antibiotic use, why wouldn't be able to evolve to overcome antibody or cell-mediated immunity?

Thanks

One possible explanation: antibiotics have only one target while vaccines elicit antibodies against multiple targets and multiple T-cell epitopes. Even more targets arise when comparing subunit vs inactivated vaccines, where the number of targets are extremely higher using inactivated vaccines, containing whole bacterial cell.