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How does the body heal a skin wound without bleeding? I had a wound in which thick layer of skin was gone and which was too painful to touch. I could see the wound secreting clear liquid rather than forming a scab like in a blood wound. What is this yellowish thick liquid being secreted and does it form new skin?

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  • $\begingroup$ The clear/transparent fluid you are talking about, is most likely serum, an amber-coloured, protein-rich liquid which separates out when blood coagulates $\endgroup$
    – Ebbinghaus
    Commented Mar 23, 2016 at 22:33
  • $\begingroup$ Jordi Zambrino-Are there 13 proteins? can you name them. $\endgroup$ Commented Mar 23, 2016 at 23:17
  • $\begingroup$ @TheVoid What are you on about? $\endgroup$
    – Ebbinghaus
    Commented Mar 24, 2016 at 19:34
  • $\begingroup$ @Jordi Zambrino- Ill ask a question on it in a bit, It has to do with the 13 protein factors. $\endgroup$ Commented Mar 24, 2016 at 21:34
  • $\begingroup$ @uncia- Was the wound around the knee area? $\endgroup$ Commented Mar 24, 2016 at 21:35

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Skin is composed of layers, the uppermost being the epidermis. Upper layers of the epidermis (dry, flat cells tightly packed together, and of varying thickness on different parts of the body) can be abraded off, leaving deeper layers of the epidermis (nearer to underlying blood vessels) exposed. Since peripheral nerve endings do exist in this area, the wound is painful. A wound that does not extend into the dermis does not bleed (for example, a second degree burn can lift the upper layers of the epidermis from the deeper layers; no blood will collect in the blister, but the wound is painful. Peel off the top of the blister, and you have an analogous situation.

enter image description here

Because the surface of the skin is no longer present, fluid (as with a blister, not containing red blood cells) leaks from the blood vessels. Initially a transudate, it can also be an exudate. And, no, it does not contain the cells needed to regenerate the upper layers of the skin. It contains many of the proteins found in serum and may contain white blood cells which help to fight off infection.

New cells are generated from the deeper cell layers (the basal cells) which are still intact. They grow from the bottom of the wound up, so to speak. The scab formed by the dried fluid keeps the layer under it moist, providing a good environment for cell growth.

Epidermis and Its Renewal by Stem Cells

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