What percentage of the human genome hasn't been sequenced yet? I have read different estimates, e.g.:

If there isn't a consensus on the percentage of the human genome that hasn't been sequenced yet, why is it difficult to estimate?

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    $\begingroup$ Why do you care if it is 5% or 6%? What are you going to do with the number, which in any case will probably have changed in 12 months time. That isn't an interesting scientific question, which is why you are unlikely to find a "consensus" — people aren't discussing it. What is interesting is nearer to your last question. Why it is difficult to estimate is subsidiary to the question why the remaining gaps are difficult to fill. I suggest you search for info on that (perhaps even here on SE Biology) and come back with a modified question if necessary. $\endgroup$ – David Jul 5 '19 at 12:23
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    $\begingroup$ @David's comment may be a bit harsh, but I think the recommendation to focus on the last sub-question as the actually interesting bit is good. Although you say there is not consensus, "4-9%" and "8%" are estimates in complete agreement with each other because 8% is in the range 4-9%. The second article you link specifically explains why this is different from the "99%" or "complete" number in your first link (99% is relative to the amount that "can" be sequenced with the technique used). $\endgroup$ – Bryan Krause Jul 5 '19 at 16:18
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    $\begingroup$ @BryanKrause I don't think that's correct: The 99% estimate and the other estimates essentially refer to the same. They are simply vastly different and contradictory estimates. In particular, the amount that “can” be sequenced and assembled has been sequenced and assembled to exactly 100%. $\endgroup$ – Konrad Rudolph Jul 6 '19 at 8:49
  • $\begingroup$ @KonradRudolph Further evidence that the interesting question is the one David suggests rather than the title. $\endgroup$ – Bryan Krause Jul 6 '19 at 9:04
  • $\begingroup$ This is likely related to long repeating sequences of DNA which are unlikely to be sequenced with current sequencing techniques. Essentially we cannot determine the number of repeats and thus we have to estimate how much of the DNA that remain unsequenced. $\endgroup$ – Jeppe Nielsen Jul 8 '19 at 1:02

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