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Tag for questions relating to the sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis. DNA and RNA molecules are written in a language of four nucleotides; meanwhile, the language of proteins includes 20 amino acids.

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How to determine the most likely reading frame of a DNA sequence?

I could also write out the translations for a given reading frame with a codon usage table. It's the most probable reading frame part I don't get. … I can only see one start codon (atg). What is the correct way to recognize the most probable reading frame? I can't find this problem exactly on Biology Stack Exchange. …
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