I want to simulate interaction between the bHLH-LZ domain of c-Myc encoded protein and a test ligand. Since the domain is intrinsically disordered, I want to generate all possible conformations of the IDP to run several iterations of simulation, each time with a different conformation. How can I do so? I would really appreciate if you could explain me what is the basis of these conformations and explain the concept?
Thank you!


Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Browse other questions tagged or ask your own question.