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Are neutrophils able to get inside epithelial cells in order to kill bacteria. Therefore, even if a bacteria gets inside the epithelial cells can the neutrophils get inside the epithelium to kill the bacteria?

Also when the bacteria get into blood stream can neutrophils kill the bacteria?

I am not from a biology background. So, a simple explanation will be helpful

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    $\begingroup$ Please do some basic reading on neutrophils (or whatever your topic is) before you post a question. We want to help clear up confusion or solve problems in people with a sincere interest in Biology. But we do ask for evidence (in the question) of what you read about it. Thanks. $\endgroup$
    – anongoodnurse
    Commented May 28, 2017 at 13:21

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Are neutrophils able to get inside epithelial cells in order to kill bacteria. Therefore, even if a bacteria gets inside the epithelial cells can the neutrophils get inside the epithelium to kill the bacteria?

No. Firstly because bacteria (except for very special cases) do not enter epithelial(or other) cells - that's what viruses do. Second, neutrophils recognise bacteria based on markers on their cell wall. These markers can come from the bacteria themselves, or from the innate immune system (see complement system) that 'marks' the bacteria, in any case being inside another cell would protect bacteria from neutrophils. Cases are like these are handled by the CD8+ T-cells of the adaptive immune system.

Also when the bacteria get into blood stream can neutrophils kill the bacteria?

Yes, that's their job and neutrophils are usually inside of the blood(stream), so they could find and kill bacteria there.

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