When hydrogen bonds happen between the RNA nucleotide bases and the DNA bases , do phosphodiester bonds form between the RNA nucleotides in the primer ? No source I read is clear about this, are their bonds between the RNA nucleotides ?

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    $\begingroup$ @Dirigible — I suspect that the poster is talking about Okazaki fragments, and wishes to know whether they are covalently linked to the growing DNA. If so, I seem to recall a similar question previously. However the question is unclear. Poster, please clarify your question and preferably present a diagram, or link to one, so we can see what aspect seems unclear to you. The accompanying text would help — it could be that rather than the texts being unclear, there is something in the explanation you are misunderstanding. $\endgroup$
    – David
    Dec 20, 2019 at 18:42
  • $\begingroup$ I have posted an answer. However, this seems like a basic question and is easily answered by consulting sources such as Wikipedia. As such I'm flagging this question as "homework" since it "addresses a basic biology concept that may seem trivial to biology professionals". ——— Please take the tour and then go through the help pages starting with How to Ask questions effectively on this site. Thanks! 😊 $\endgroup$
    – tyersome
    Dec 20, 2019 at 20:46

1 Answer 1


A primer is by definition a short single strand of nucleic acid (i.e. a series of nucleotides linked together by phosphodiester bonds). See also this wikipedia article.


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