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5 votes
1 answer
3k views

How to determine the most likely reading frame of a DNA sequence?

This question is from a past exam paper for an introductory bioinformatics module. I'm a computer scientist doing biology for the first time. "A short bacterial gene has been sequenced, giving the ...
azure_reflection's user avatar
1 vote
1 answer
298 views

Does an ORF need a stop codon?

I try to read ORFs from a gene sequence but I am not sure how to interpret a sequence with a start codon but no stop codon. Imagining I have a gene sequence like the following: ...
yemy's user avatar
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