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A post-transcriptional mechanism of gene-regulation/silencing mediated by small interfering RNAs (siRNA)
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Where in the cell does this enhancer RNA knockdown take place?
In Pnueli et al., 2015, they knock down an enhancer RNA using RNAi, testing whether it is a mere byproduct or whether it has a key role in the enhancer's function. They find their system works: the si …