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The study of the molecular structure of biological macromolecules and how that structure relates to their function.

5 votes

Topology of closed circular DNA

DNA is not always negatively supercoiled naturally. It is important to keep in mind that different regions of topologically constrained DNA can have different supercoiling values. For example, the act …
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1 vote

Why does sequence of amino acids presented on the Catalytic Site Atlas from a given protein ...

This answer is correct, I just wanted to add that the correct sequence numbering is preserved in the PDB file in the DBREF record (which you can see by opening the PDB in a text editor): DBREF 3NOS …
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2 votes

Are there functional examples of parallel DNA double helices?

All articles I found discussing parallel helices are purely speculative with regards to biological significance; but, they are still interesting. Here are some that I found, in addition to the other a …
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7 votes
Accepted

Twist in the DNA double-helix

First, your description is accurate. The only pedantic critique I would make is that the technical term for nucleotides in DNA is deoxyribonucleotide. Second, I don't want to say that non-helical DNA …
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3 votes
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At what point, when connected, do DNA strands become a helix?

In general, a single stranded nucleic acid is helical in the absence of other secondary structure. The base stacking that drives helix formation does occur between adjacent bases in the same strand. …
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51 votes
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Does any molecule other than DNA have a double-helical structure?

A few examples: Starch A polymer of glucose that can form a double helix and functions primarily as energy storage in plants. [image source] f-Actin Filamentous actin forms a helical structure with …
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