3
$\begingroup$

What is the difference between Endoproteinase Lys-C and Lysyl endopeptidase?

In the text I'm translating about peptide mapping, "lysine protease" is mentioned (in Russian: лизиновая протеаза). This might be erroneous to translate word for word as "lysine protease". There must be a slight error in the original text. This "lysine protease" is mentioned there due to its use in protein hydrolysis.

I guess that the correct translation might be either endoproteinase Lys-C or lysyl endopeptidase.

I found that endoproteinase Lys-C is used in peptide mapping. Is it synonymous and interchangeable with lysyl endopeptidase, or do they differ in their function? Is endoproteinase Lys-C used more often as a hydrolysis agent in peptide mapping?

Maybe the difference is that endoproteinase Lys-C cleaves "on the C-terminal side of lysine residues", while lysyl endopeptidase cleaves on both sides?

$\endgroup$

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Browse other questions tagged or ask your own question.