I was looking at some Olympiad questions and came across the following:

If the frequency of a completely recessive allele is $0.2$ and it remains unchanged from generation to generation due to superior fitness of heterozygotes, then find the intensity of selection against the dominant homozygotes.

As far as I know, selection intensity is a quantitative measure of the superiority of the individuals selected for breeding. However, I am not really aware of how to compute its numerical value.

The best I could do was to assume that the frequency would be a ratio of the selection coefficient of recessive homozygotes ($s$) to that of the sum of selection coefficients of both recessive ($s$)and dominant homozygotes ($t$), i.e. $\frac{s}{s+t}$, but that doesn't seem to lead me anywhere. Also, I can't think of a concrete reason as to why the frequency would be of this form if it is actually.

Any suggestions/pointers would be much appreciated.


Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Browse other questions tagged or ask your own question.