Please explain what the term synaptic clearance means. For example, what would dopamine synaptic clearance be? It is important to me in context of dopamine signaling variation due to difference in synaptic clearence level.
Some gene alleles are associated with greater synaptic clearance in dopamine pathways. It used to explain dopamine level variation and throught it some brain areas activity (for example Nucleus Accumbens) difference among people with different genotypes. For more information see for example. Also, reduced synaptic clearence related to greater dopamine signaling levels. So I was interested in this term from prespective of brain activity in areas with dopamine receptors