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A computational model is a mathematical model in computational science that requires extensive computational resources to study the behavior of a complex system by computer simulation.

4 votes

Scoring matrices (BLOSUM & PAM) in BLAST and other sequence-comparison programs

A scoring matrix is used to compute a score for finding identical 3-letter words or similar 3-letter words that takes into account the liklihood of one being related to another. Although these matrice …
David's user avatar
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3 votes
Accepted

Role of Automata Theory in Biology

Interpretation of the question From the responses of the poster to questions in comments and the revision of the question my understanding of the comparison it makes is as follows. The the structure …
David's user avatar
  • 26.6k
3 votes

Is it possible to create a restriction map using python?

First I'll answer this question on the assumption that you are learning or about to learn python (perhaps because you have heard it's become popular in bioinformatics) and you wish to know whether it …
David's user avatar
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2 votes

Can exhaustive algorithms produce MSAs that are suitable for 3D structure modelling?

No. Methods for multiple sequence alignment (MSA) like T-coffee, which you mention, and Clustal (http://www.clustal.org), which is also widely used, employ heuristics for the alignment for the very …
David's user avatar
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