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Results tagged with cancer
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user 819
A malignant group of uncontrollably dividing cells that form a tumour. Questions regarding (proto)oncogenes and tumour-suppressor genes should also use this tag.
1
vote
Accepted
What specific mutations can cause an apoptosis mechanism to malfunction?
There are lots and lots of specific single mutations that cause problems with apoptosis.
Some of the most common are in P53, PTEN, MYC, APC, and KRAS. If you want a specific amino acid change, KRAS G …
- 617
6
votes
Accepted
How similar are Circulating Tumor Cells and Cancer Stem Cells?
There are several competing models of metastasis, and this question does go right to the differences between them.
The primary thing to remember about CSCs is that all evidence suggests that they are …
- 617
1
vote
Deciding a reasonable threshold for copy number variation in a CNV (SNP array) TCGA dataset
Your suggested approach of comparing to the baseline distribution on a point-by-point basis isn't bad, although it's going to be susceptible to small false positives from noise. You'd probably want to …
- 617