All Questions
5 questions
0
votes
1
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111
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Get "DNA" of one parent based on its children [closed]
I'm no biology expert so bear with me, but I've been given a task to estimate alleles of an animal based on the animal's children and the children's other parents.
I've looked up Mendel's laws but I'm ...
- 111
1
vote
2
answers
477
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GEN file format, SNPs and alleles
I have a few questions I can't seem to get a straight answer to, regarding the .gen file format and also biology in general.
The ...
- 123
0
votes
3
answers
254
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why and how multi allele gets reported during variant calling in vcf?
This might be a very basic question for many here. With the basic understanding of inheritance, eventhough there is a possibility of multiple genotypes due to multi alleles, the resulting genotype can ...
- 101
4
votes
0
answers
667
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Minor Allele Frequency (MAF) higher than 0.5? [closed]
I have a set of data in PLINK format (*.bed, *.bim and *.fam files). There are around 2000 individuals in my dataset.
I used PLINK to calculate allele frequencies in the population:
...
- 41
2
votes
0
answers
76
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What is the best test for SNV clustering?
I am looking for a method to cluster single nucleotide polymorphisms based on clinicopathologic data (mainly receptor immunoistochemistry). So far, I've came up with only two that handle dummy ...
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