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1 vote
1 answer
41 views

Can oxytocin travel from one cell to another via gap junctions?

Oxytocin is a 9-residue secreted peptide. As a hormone, can it travel through gap junctions, assuming that it is stored in pre-synaptic neuronal vesicles?
0 votes
1 answer
307 views

Can caffeine act as viagra

Recently I studied that cAMP which is a 2° messenger can cause various physiolocal changes under the action of proper hormones. Now cAMP is degraded by phosphodiesterase and this ceases the actions. ...
5 votes
1 answer
2k views

How is adrenaline (also known as "epinephrine") a ligand?

I keep reading that adrenaline is a ligand, however, from what I understand a ligand is a molecule or ion which donates a pair of electrons to a central transition metal ion in a complex. If this is ...
2 votes
1 answer
132 views

How is insulin transported in vivo in mammals?

What is the mechanism for transport of insulin in mammalian cells?
3 votes
0 answers
314 views

How does estrogen influence collagen synthesis?

Through what mechanisms does estrogen interact with collagen synthesis? Especially in the context of elevated estrogen levels and genesis of purpura simplex .
3 votes
1 answer
102 views

How do you express and detect GLP-1 receptors?

I am currently working with a peptide which is an analogue for glp-1, but during invitro studies am not able to detect for the presence of GLP1- receptors. The cell line used is Min-6. How do I detect ...
7 votes
1 answer
75 views

circulating microRNAs are functional?

In plasma and other body fluids, miRNAs can be found. They not only originate from dying cells but also from active secretion and are usually 'packed' into vesicles/lipo-proteic structures (i.e. ...