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0 votes
1 answer
86 views

Gene Mapping - Please explain in Lay terms

Taking an AP bio course, and for some reason I cannot comprehend the mechanism of how one determines the location of alleles on a chromosome. The math is simple and I can memorize it, but its bugging ...
0 votes
1 answer
66 views

Mechanism of random assortment of chromosomes

How does the random assortment of chromosomes during meiosis occur? I am a mathematician, not a biologist, and I am surprised that it is difficult to find an answer to this question online (AI ...
3 votes
1 answer
287 views

Recombination Data Set

I was looking over some genetics question and came across this data set. In the fruit fly Drosophila melanogaster there is a dominant gene b+ for grey body color and another dominant gene c+ for ...
0 votes
1 answer
56 views

How frequently does recombination occur, and how long are the recombinated fragments?

I understand the mechanics of recombination, but am struggling with the 'scale'. When two homologous chromosomes pair, roughly how many recombination events occur on average? I understand there will ...
1 vote
1 answer
45 views

How to disambiguate between chromosome and chromosome pair?

Our genetic information is stored in 23 pairs of chromosomes that vary widely in size and shape. Chromosome 1 is the largest and is over three times bigger than chromosome 22. Source: https://www.ncbi....
0 votes
1 answer
340 views

Why is There a Necessity for Two Rounds of Cell Division and Four Daughter Cells in Meiosis

Why does meiosis involve two rounds of cell division instead of stopping after meiosis I, where each daughter cell would have one chromosome randomly selected from each pair of homologous chromosomes? ...
9 votes
1 answer
4k views

What determines the number of chromosomes an organism carries?

This is an extension of this question about What limits chromosomal length?. I am wondering what could be the specific reasons behind the number of chromosomes an organism carries. In other words, ...
-5 votes
1 answer
125 views

Is it possible to separate either father or mother chromosomes from a sperm? [closed]

If we were to use a flow cytometry, can it separate either the father or mother chromosomes from a sperm?
2 votes
0 answers
190 views

If crossing over did not occur, would pairs of cells after meiosis II have the same genes?

If crossing over did not occur, would there be two pairs of cells with the same chromosomes after meiosis II? This question came to my mind while I was reading through my bio textbook. After meiosis I,...
2 votes
1 answer
513 views

Maximum number of chromosomes a human can have without dying? [closed]

I know that trisomia of chromosome 21 gives a person the Down's syndrome. Sometimes one can have sex-chromosome trisomia, and it is not apparent until adolescence. Certainly none of those problems ...
2 votes
2 answers
1k views

Question about Autosomal Recessive Alleles

I had a homework question that I could not figure out. It states: A woman has cystic fibrosis in her family and did not want to have a child that suffered from the disease. She and her spouse ...
2 votes
0 answers
64 views

What is the DNA sequences between two Inverted Repeats called?

I would like to know some rules about the nomenclature of Inverted Repeats DNA sequences. More in detail, I want to know what is the name of sequences between two inverted repeats. For example, I have ...
0 votes
1 answer
200 views

Could someone explain how chromosomes are counted here?

I'm not sure how chromosomes are counted in this picture. I would reason that there would be 8 chromosomes in the diploid cell, but that doesn't seem to be the case. Could someone explain?
10 votes
1 answer
208 views

What causes cells to inactivate one X-chromosome?

Normally, when a cell has two X-chromosomes (female genome), one is randomly inactivated. How does the cell detect that there are two X-chromosomes in the first place? Is there some kind of protein ...
1 vote
1 answer
189 views

How is it determined whether a chromosome is maternal or paternal for imprinting?

For imprinting, how does the cell determine which chromosome is maternal and which is paternal? For example, in the parental imprinting of insulin-like growth factor 2 (Igf2) on chr7 (autosome), how ...
5 votes
1 answer
27k views

What are homologous chromosomes?

I've read that homologous chromosomes are composed of one maternal chromosome and one paternal chromosome. I want to confirm if this image is for one set of homologous chromosomes: They have the ...
6 votes
1 answer
149 views

Why are Chromosome Territories important?

Chromosomes occupy discrete regions of the nucleus, referred to as 'Chromosome Territories'. This spatial organization is emerging as a crucial aspect of gene regulation and genome stability in health ...
0 votes
0 answers
299 views

Why do chromosome pairs have different shapes and sizes?

When I look at microscopic images of human chromosome pairs I see that they have different shapes and sizes. Is there a deeper biological reason for that? Is there some evolutionary pressure for them ...
0 votes
2 answers
57 views

Chromosomal disorders

I was reading about chromosomal disorders and encountered a line stating that 'An individual may lack one of any one pair of chromosomes' So does it mean that an individual cannot have monosomy of ...
3 votes
2 answers
463 views

Human ancestor reproduction after chromosome fusion

I read somewhere that human chromosome 2 is the result of 2 primate chromosomes fusing together somewhere along our evolutionary journey. This is why we have 23 chromosomes while other primates have ...
-2 votes
2 answers
2k views

Barr body Giemsa staining

Not all the female cheek cells show Barr Bodies when stained with Giemsa stain? Only 30 to 40% female cells show Barr Bodies. Why? Our Experiment: We washed mouth twice with listerine to reduce ...
0 votes
1 answer
180 views

What is a proximal deletion breakpoint?

I am reading a journal paper about the relationship between NCAM2 and autism. I have come across the following statement in the paper: Based on analysis utilizing the UCSC Genome Browser (hg18, build ...
0 votes
1 answer
90 views

Do we come to know which allele is dominant by seeing family genration tree only?

I know that a Gene has Alleles (variation) and one is Dominant over Other i.e the Other Recessive. Then I got a Thought that How can we tell whether an Allele is Dominant or Recessive...... and I came ...
0 votes
2 answers
130 views

What is the chance a given gene will end up in a given gamete?

Let us say a germ cell had a desired allele. This germ cell was replicated during interphase so that it had two of the desired allele. It then underwent meiosis. My question then is, what is the ...
6 votes
4 answers
7k views

The human has 46 double chromosomes or simple chromosomes?

What I mean: does the human cell have 46 of these: or 46 of these: Thank you in advance.
1 vote
0 answers
36 views

chromosome 19 and recombination

Im doing a project with structural variation created by recombination within the human genome during spermatogenesis, where im especially examining intrachromatid homolog recombination. I find that ...
4 votes
1 answer
94 views

Chromosome naming convention: Why are there chromosomes named "1" and "1A"?

I've been stumbling on multiple genome of birds where there is a "1A" chromosome and a "1" chromosome. For example, the zebra finch has 1A and 4A. What does that mean? Do you have any resource about ...
0 votes
1 answer
200 views

What is the Definition of Homologous Chromosomes? length, gene position are the same or similar? [duplicate]

what is the Definition of Homologous Chromosomes? this post says Homologous chromosomes are chromosome pairs (one from each parent) that are similar in length,...
0 votes
0 answers
134 views

Number of DNA strands per chromosome

As I was reading Griffith's Introduction to genetic analysis this evidence was provided for single DNA makes single chromosome. Eventually geneticists demonstrated directly that certain chromosomes ...
0 votes
1 answer
212 views

Possible combinations in the Meiosis' Telophase 1

As you might already know Meiosis is the process in eukaryotic, sexually-reproducing animals that reduces the number of chromosomes in a cell before reproduction $^{[1]}$ One of the reasons why ...
13 votes
1 answer
1k views

Why does size decrease across the sequence of human chromosomes?

The following graph shows a decrease in the number of base pairs per chromosome across the sequential set of human chromosomes: Is this because chromosomes were originally numbered by their size on ...
16 votes
5 answers
12k views

Do men and women have the same number of genes?

As far as I know, humans have 23 pairs of chromosomes, each one which contains a particular amount of genes. But in the "last" pair, men have a XY pair chromosome, and women have a XX pair chromosome. ...
-1 votes
1 answer
727 views

The organisms of the same species with a different number of chromosomes [closed]

I am looking for some specific creatures. The organisms of the same species that have different chromosome numbers. Just like male grasshopper (23 chromosomes) and female grasshopper (24 chromosomes). ...
1 vote
2 answers
4k views

Why are GC-rich regions less condensed than GC-poor regions?

As far as I know, chromatin consists of two kinds: Heterochromatin is more condensed so translational factors have less access to this region, and this region is poor in GC. Euchromatin is less ...
3 votes
0 answers
58 views

Offspring of parents with different number of chromosomes

Many papers report that dog-whelks (Nucella lapillus) show a distinct chromosomal polymorphism between populations of 2n = 24 up to 2n = 36. Could somebody please tell me how many chromosomes the F1 ...
1 vote
1 answer
3k views

Do chromosomes line up as pairs in mitosis or meiosis?

Here is a question from the book SAT II Success Biology E/M (where the SAT is the exam taken by the American high school students): Homologous chromosomes line up in pairs in (A) metaphase of ...
1 vote
1 answer
264 views

How do parents give their offspring a chromosome?

Whenever an organism sexually reproduces, it gives its offspring one chromosome from each of its pairs of chromosomes. My questions are Is this done randomly? Is it uniformly random? If so, what ...
1 vote
1 answer
2k views

Genotypes of gametes produced by an F1 individual?

I have an urgent question as I have an exam tomorrow. I was skimming some past exam papers and one question came up which has me completely confused. A cross was made between a pure breeding diploid ...
0 votes
1 answer
72 views

Are there chromosomes that we inherit that are not recombinated? [closed]

We do have chromosomes that recombinated ,but aren't there pure chromosomes that are not recombinated that people would have?
2 votes
1 answer
349 views

How do the chromosomes arrange themselves after fertilization in humans?

In human reproduction the male produces sperm containing 23 chromosomes and the female has the oovum containing 23 chromosomes , so after fertilization the zygote contains 46 chromosomes. What I want ...
1 vote
0 answers
36 views

Did the chromosomal fusion within humans affect phenotypical change compared to the separated chromosomes in the other apes?

I just read this article on the evolutionary divergence between humans and chimps, and how the most significant event was when the 24 number of chromosomes in chimps was reduced to 23 in humans due to ...
6 votes
1 answer
7k views

Examples of animals with different number of chromosomes that can interbreed?

When I was first started to write this question, I wanted to know how species evolve to have a different chromosomal arrangement, such as having two pairs of chromosomes instead of one? However, I ...
0 votes
1 answer
109 views

What exactly happens during the crossover [closed]

My knowledge of biology is rather limited, but I think I have a grasp of some basic concepts. For me (as a person close to math) a chromosome is a sequence of elements from the set {A,C,T,G} of some (...
3 votes
4 answers
18k views

Why does autosomal trisomy have more adverse effects than sex choromosome monosomy or trisomy?

Autosomal trisomy syndromes are usually lethal but sex chromosome number related abnormalities do not lead to that much fatality. why?
2 votes
2 answers
804 views

Why the genome is divided into several chromosomes and not just a single big chromosome?

In many eukaryote species, there are several chromosomes. In humans, for example, there are 23 pairs of chromosomes. Why are there several chromosomes and not just a join of all chromosomes into a ...
0 votes
1 answer
70 views

On what basis is each chromosome given a number? [duplicate]

On what basis is each chromosome given a number? There appears to me to be no visible ordering between each pair. Is there any reason other than differentiation?
1 vote
0 answers
173 views

Coefficient of relatedness for a locus on the Z chromosome

So i know that the ZW determination system is the equivalent for XY in birds. Moreover, I know that the coefficient of relatedness between siblings for the X chromosome is 0.5 so im guessing that the ...
10 votes
1 answer
7k views

Which of the two chromosomes in a pair is expressed?

I have completely dummy question. I have 23 pairs of chromosomes in the cells 23 single coming from my mother and 23 single from my father. So how my cell choose which chromosome, mother's or father'...
1 vote
1 answer
134 views

What is linkage?

If two genes are on the same chromosome, are they always “linked”? What if they are more than 50 cM apart? Then they would follow Mendalian pattern of inheritence. So are they still linked?
4 votes
3 answers
191 views

Can chromosomal crossover undo itself?

If I have alleles AB on one chromosome and ab on another, and if A and B are far from each other (and also a and b), then there is a lot of chromosomal crossovers happening. If I crossover 7 times, ...