All Questions
Tagged with genetics human-biology
159 questions
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Lyonization in individuals with Turner syndrome
As people with Turner's syndrome have XO chromosomes, does the lyonization of the single X chromosome take place in the somatic cells? Is this one of the reasons for the abnormalities associated with ...
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Is it possible for a non-self antigen to NOT be recognized by the body?
The amazing diversity of antigens that the body can recognize (by virtue of T and B cells that express receptors complementary to them) is truly fascinating. The explanation mooted for this is the ...
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Can the effect of an allele on height be context-dependent?
Some data is available on the effect alleles have on height. For example Common DNA Variants Accurately Rank an Individual of Extreme Height
However after browsing the literature I was not able to ...
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Can We Determine the Cell Types Ab initio?
Is it possible to find all cell types in the human body and their respective transcriptomes by analyzing the human genome (and doing no physical experiment)?
If such a thing is possible in principle, ...
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Can DNA test of my grandparent's brother reveal my heritage from that branch of the family?
I'm thinking about doing that DNA test on all my grandparents to know where their genes come from. They are getting very old and I don't want to let the opportunity pass to gather more knowledge about ...
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How many genes of an individual are homozygous?
We have 20000 to 25000 protein-coding genes. Considering an individual, how many of his\her protein-coding genes are homozygous? I am looking for an estimation of gene homozygosity ratio in human ...
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Monozygotic vs Dizygotic heteropaternal superfecundation
Update: I had a wrong assumption.
After triple checking, I now see that how ordinary monozygotic twins arise is 1 sperm and 1 ovum and then later the zygote splits up.
(1.1. and that that phil and ...
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The village of Twins — Mystery behind and Scope
With the presence of more than 200 twins, Kodinhi , a village situated in Malappuram District in Kerala , India , is popularly known as the "Village of Twins".This phenomenon of large ...
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Is it possible to fuse DNA from two sperms and can a baby be born from that? [closed]
If this is possible, then isn't there going to be a chance to have a YY child?
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Why do humans share over 99% of their genomes?
From Wikipedia
The haploid human genome (23 chromosomes) is about 3 billion base pairs long and contains around 30,000 genes.[33] Since every base pair can be coded by 2 bits, this is about 750 ...
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Are there any phenotypically visible examples of gene linkage in humans?
Are there any examples of two "visible" or "obvious" phenotypic traits in humans that are a priori unrelated, but which tend to be inherited together (i.e. their inheritance ...
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Advantages of pain sensation?
The hazards of congenital insensitivity to pain (CIP) are well-known.
This question is about the obverse: what selective advantage, if any, does the normal sensation of pain confer? I'm thinking of ...
CommunityBot
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How do you determine "in which direction" DNA is shared between groups of people
In popular DNA ancestry tests you can read lines like "you have 2% neanderthal dna" or "you have 20% italian". How can you distinguish between a person having 20% italian vs ...
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Why is haemophilia unviable in later stages of life?
A sentence in my textbook is:
The possibility of female being haemophilic is extremely rare because mother of such a female has to be at least carrier and the father should be haemophilic (unviable ...
CommunityBot
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Walk me through microsatellite markers and PCR
Three polymorph microsatellite markers are used to try and narrow down the location of a disease locus, with the use of PCR with 2
flanks on each side of the actual polymorphic area. The PCR product ...
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Do I not have any alleles from my mom's mom & my dad's dad?
So, I have an XX, & I got an X from my mom, & an X from my dad. My dad would have gotten his only X from his mother, & my mother could have gotten the X I got from her father or mother. ...
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What is the chance a given gene will end up in a given gamete?
Let us say a germ cell had a desired allele. This germ cell was replicated during interphase so that it had two of the desired allele. It then underwent meiosis.
My question then is, what is the ...
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Why is cognitive maturity related to organism lifespan in larger animals and mammals?
I am not a student of biology, so I should provide some context to me asking this rudimentary question. While doing a graduate-level course on Reinforcement Learning, the instructors focused on how we ...
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Is it true that if a human lived long enough (up to 3-400 years), he/she would eventually develop cancer?
I have just studied DNA, but I am not so clear. So, I would like you to explain it more clearly.
This is what I think when a human grow older and older, his or her DNA repair mechanism would be ...
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How does an antisense RNA molecule restore protein function in CF patients?
I am researching a treatment for cystic fibrosis (CF) called Eluforsen and I am trying to understand the mechanism by which an RNA molecule can restore proper protein function. In many research ...
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Is the lac operon repressed in the presence of both glucose and lactose?
In the presence of both sugars (glucose and lactose) will there be repression of the lac operon completely?
I know that more glucose means less cAMP --> less CAP --> less positive regulation, and ...
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Brain evolution in the age of the caesarian
I have just been reading an account of the evolution of human intelligence in Matthew Syed’s recent book on diversity, called “Rebel Minds”.
He is not the originator of this idea, but he suggests ...
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Is it possible that by mutation a human could see infrared or other 'colours'?
Incoming light reacts with the several types of cone cells in the eye. In humans, there are three types of cones sensitive to three different spectra, resulting in trichromatic color vision. Each ...
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What was the biological mechanism that allowed Tarrare to eat so much?
Are there any conjectured mechanisms that cause Tarrare's extremely oversized stomach and abdominal cavity? Along with his superhuman appetite of course. Whether from a medical perspective or a ...
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Does intelligence depend more on environment than on genetic factors? [duplicate]
Many have argued that the test of IQ is simply a test of language. The application of the test consists of asking a number of questions. The person should understand the question presented to them and ...
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115
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What could humans do to "see" what dogs smell?
We're able to see a lot of things using computers that we can't see normally: yellow-green, UV light, X-rays, etc. What do we have that harnesses the ability to "see" what dogs smell (e.g., harnessing ...
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Why do I have 95% of chimpanzee's DNA, and only 2% of Neanderthal's DNA? [duplicate]
Excuse me if it is a question with a simply answer, but I don't understand these discoveries, looking a discrepancy from my unknowledge of genetics:
I have 95% of Chimapanzee's DNA,
and,
I have [...
CommunityBot
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How many genes do we share with our mother?
Somewhere I have read we share more than 99% of our genes with every other other person and 98% of our genes with chimpanzees. What does this mean? Don't we share 50% of our genes with our mother and ...
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Why isn't the human zygote considered a human life how is a living anatomically modern human defined biologically? [closed]
It has 46 chromosomes by default when healthy(Differences almost always are pathological) and has almost every biological functions, processes a Newborn or and Adult person has.
It even invades ...
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How can a child be blood type AB, if both of the parents are blood type A?
Basically, both of my parents are blood type A (both are confirmed and it's also certain both of them are my biological parents). I recently found out my blood type is AB. How is this possible? I ...
CommunityBot
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1
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Left and Right Handedness
Today I found out that the gene for being Left-handed is dominant while Right-handed is recessive. I personally am left handed and so is my father. My mothers father is also left handed and I was ...
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Are all genes transcribed in differentiated cells?
My textbook tells me that it’s specific transcription factors that allow for a different set of genes to be expressed in different cells (differential gene expression). My book gives the example of ...
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is it possible for a son to inherit an allele on a Y chromosome?
Obviously, the only way for one to be male is to inherit the Y chromosome, but are there alleles on the y chromosomes? Or is it just automatically the recessive trait without an allele.
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Understanding genetic similarity in humans [duplicate]
I was reading "Blueprint" by Robert Plomin (online preview on webpage) and got stuck when I got to these two sentences in the prologue:
"We are the same as every other human being for more than 99 ...
- 7,716
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87
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The space of all human DNAs [closed]
This is both a math and biology question but I think it makes more sense for a biologist to answer it. My question is: what can be said, if anything, about the space of all possible human DNAs (for a ...
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Why can't this be 1st meiotic division non-disjunction as well?
The child has gotten 2 "sick" chromosomes from his dad and 1 healthy from his mom, leaving it with trisomy 13.
I can see how this can happen in the second meiotic division of the father but ...
CommunityBot
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Do men and women have the same number of genes?
As far as I know, humans have 23 pairs of chromosomes, each one which contains a particular amount of genes. But in the "last" pair, men have a XY pair chromosome, and women have a XX pair chromosome. ...
- 534
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How can a chromosome translocation in somatic cells lead to disease?
Looking at this picture...
(source: nih.gov)
...I get the impression that the part of chromosome is attached to other chromosome, but it is not mutated. When we assume that all genes in the ...
- 579
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Can I train my non-dominant hand and make it dominant?
Are our dominant limbs decided on birth or is there some way in which I can train my non-dominant hand and make it as coordinated as my dominant?
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Are all genetic disorders inherited?
I know that genetic diseases such as cystic fibrosis are often passed down through generations and are therefore classified as genetic disorders, but if a mutation occurs spontaneously, which for ...
CommunityBot
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Have there been new discoveries concerning the perception of taste for the last 10 years? [closed]
What are the last discoveries concerning the perception of taste for the last 10 years?
We discovered the 5th flavour: umami.
Also the 6th and 7th: oleogustus and starchy.
Anything else?
Maybe in ...
CommunityBot
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Would our body adapt to changes that are not in our DNA?
If a person was to undergo a treatment or surgery at a very young age, that significantly reduced their final height, would the rest of their body adjust to the sudden change? If not; because our arms’...
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Does low gravity exposure to early stages of human fetus have potential to unloc unused genetic information from earlier stages of evolution?
The title seems quite self explanatory but let me elaborate.
New mutations do take a very long time and many generations to occure in the genetic code. But our genetic code already holds all the ...
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446
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Knockout and knockdown of gene
Out of curiosity, I got this question whether knocking out (deletion) of a gene on one side and knocking down (RNAi) of the same gene on the other side will affect the cell in a similar manner or not.
...
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Will our biological bodies be changed after we’ve occupied and settled Mars? [closed]
I had this question in mind for very long time, and I could not find a clear answer on the Internet, so I was hoping that you might know the answer.
If we will bring life to planet Mars and a few ...
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Are modern gene-editing techniques capable of creating genetically-superior versions of humans? [closed]
Can we alter the DNA in, say, a small-framed, low muscle mass male to those of elite bodybuilders?
Can we alter the DNA sequence that stops balding and hair loss? How about the genes responsible for ...
- 3,645
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364
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Is marriage with half-cousin's daughter more risky than marriage with others?
I want to know is marriage with half-cousin's girl more risky than marriage with a non-family girl?
Also I like to know if her parent are cousins(but from mother side), does it add more risk to this ...
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How do you write genotypic and phenotypic ratios?
If two homozygous recessive parents are crossed, I know that all of the offspring will be homozygous recessive as well. Would you write the genotypic ratio as 0:0:4 then and the phenotypic as 0:4? (...
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Does the deletion of Chromosome 20 cause immunity against prion disease?
I was reading recently about prion disease and it caught my attention that a normal prion protein is coded n chromosome 20, therefore, in order for an infectious prion protein to attack, there must be ...
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3
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Why is the mechanism of inheritance for this disease autosomal dominant?
An unrelated couple has a daughter and a son with the same rare condition. Neither parent has any obvious signs of the condition, but the father's mother (paternal grandmother) and her brother have ...
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