Questions tagged [coronavirus]

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0answers
20 views

Can we use ultrasound to disable/denature viruses such as COVID

Can we use ultrasound to create a resonant frequency to that of the molecules within the shell of the covid-19 virus and cause them to "shatter" just like a wine glass and an opera singer. I ...
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1answer
59 views

Why doesnt the SARS-Cov-2 affect other animals?

Why doesn't the coronavirus affect animals like dogs and cows? I know that the SARS-CoV-2 is a zoonotic virus i.e. it can affect both humans and other animals. I also know that the DNA composition ...
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34 views

How are stem cells used against Covid? [closed]

I read that Trump was cured by some 'drugs' using stem cells. What is the methodology behind?
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35 views

RNA vaccination and Autoimmune Reactions

To my knowledge we do not have any robust experience with RNA vaccination. Most likely this will change in the near future as RNA vaccines against COVID are in the pipeline. The rationale behind this ...
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2answers
152 views

Is the coronavirus getting less dangerous?

Please note This question is based on data from the UK government's web site (data from the ONS). I am not taking this data as accurate, but am using this as it is the only source of data I can find, ...
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Are lockdowns good or bad? What is the scientific consensus, if any?

I thought doctors support lockdown measures and populist politicians oppose them, but then this "Barrington Declaration" cropped up and I don't know what to think now. Are lockdowns good or ...
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1answer
62 views

COVID-19 deaths by year of birth?

Are there (global, country, etc.) data of COVID-19 deaths (or hospitalization) by year of birth? I was able to found them only by "age group", the meaning of this being usually an interval ...
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1answer
57 views

Why do coronavirus cases graphs have a sinusoidal like shape?

Some screenshots from a canadian website: See this sinusoidal shape? Why is it there? Shouldn't it be a single curve? My main guess is when cases are counted: is it possible that they are counted ...
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59 views

Biosafety Level 1 (BSL-1) surrogate viruses that show greatest similarity to SARS-CoV-2

I would like to know if there are any viruses that show high similarity to SARS-CoV-2 (particularly in terms of structure) that are very safe to use (i.e., classified as BSL-1). For example, an avian ...
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1answer
93 views

Are coronaviruses gaining an evolutionary advantage?

So there are 7 known strains of coronavirus that are known to infect humans: 4 that cause the common cold (229E, NL63, OC43 and HKU1), and 3 that have been known to cause acute respiratory infection (...
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3answers
124 views

Is a virus a poison?

I've understood that a virus is not a living organism (like e.g. a bacterium). From Wikipedia I get that a poison is a substance that reacts physically or chemically with molecules in the human body. ...
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24 views

With the 5$ covid19 test - an antigen test - , would trials (most likely) be independent?

Actual question What would typically cause antigen tests to give a false positive or false negative and would these causes be typically independent (if we run the test twice it won't automatically ...
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2answers
43 views

What specific markers does a Covid-19 PCR test look for?

I've done a search and can't find anything as to what specifically makes a Covid-19 positive that identifies it as unique. I would expect to see something like this: https://madridge.org/journals-...
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9 views

What does the decline of serum antibodies after infection mean for B cell immunity, exactly?

About a month ago there was a small media blip about a report in the New England Journal of Medicine that neutralizing antibodies to SARS-CoV-2 decline significantly within a matter of months. ...
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1answer
53 views

How the vaccine based on “non replicating viral vector” is produced?

As I understand, this kind of vaccine is a virus that can infect the cell, start synthesis of proteins encoded by its genome, but cannot finish the replication cycle till the proper end. It can have ...
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48 views

Testing a COVID-19 vaccine on a large sample space of population from different nationalities

I came across an article few days ago, while checking the number of canditates for vaccines about COVID-19 where Sinopharm's vaccine development's trial phase caught my eye. The article says that: In ...
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1answer
73 views

Can you still contract a disease after being vaccinated and be able to spread it?

I assume I know the answer to this already but wanted to confirm before I respond to someone that appears to be arguing that vaccines don't make you immune (they only stop your symptoms?) - but you ...
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1answer
29 views

Truncated ORF3a protein of SARS-CoV2! Why? How does it formed?

Across the world so far, we have three truncated ORF3a proteins in SARS-CoV2 in India only. Can you illuminate me how does a protein (here accessory protein of SARS-COV2) generally get such nonsense ...
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16 views

How are latence period and duration of infectiosity defined?

I assume that infectiosity of an individual is not a binary property but a quantity that grows and decays gradually, very much like the number of infected or infectious individuals in a population. ...
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1answer
71 views

What kind of people are more likely to catch COVID-19?

It is well known that people of old age or with respiratory problems are more vulnerable by the effects of COVID-19. However, I wasn't able to find information on any similar trends on catching the ...
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1answer
53 views

How T-Cell recognizes a cell infected by a virus?

According to few articles I read (like BBC about The people with hidden immunity against Covid-19 ): starting out about four or five days after infection, you begin to see T cells getting activated, ...
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1answer
40 views

How close is the U.S. to herd immunity, assuming long-term immunity?

Assuming: infection always results in death or immunity (unproven, but no evidence of repeat infections yet) official COVID-19-related death counts are accurate (142k at the time of this question) ...
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1answer
35 views

Where can we see professional discussions about vaccine development of the covid-19?

Is there any place where people keep talking about the vaccine development professionally? I need the latest news.
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2answers
94 views

Can we develop a virus which is amicable for us but deadly for SARS-CoV-2 and HIV?

I am not biologist and do not have special education in it etc. It is know that in the wild, some species have their deadly enemies. What I am suggesting is can we humans find/create virus that is ...
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1answer
74 views

If Covid antibodies disappear after 2-3 months, will a vaccine still be effective?

It looks like there have been studies in China and also in Spain that suggest antibodies don't last very long or could disappear after some time. What does this mean for the effectiveness of a ...
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1answer
47 views

About how many covid-19 virus particles is required in the human body before infection and sickness follows?

Our immune systems are often able to destroy germs and virus particles. About how many of them does it take to make a 70 year old healthy male sick ? Any ideas ?
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Are SARS-CoV-2 virus particles really able to travel through filopodia and “emerge from the tips”?

Watching the new University of California San Francisco video Coronavirus forces cells to produce tentacle-like structures that infect neighboring cells I saw The growths spread out, and ...
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1answer
74 views

Did most pandemics originate from Asia/China?

This question may be on the borderline of well-posed-ness. Let me ask it. Then please tell me if or where it can be improved. Is it statistically true that the majority of the pandemics or epidemics ...
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0answers
73 views

For how long viruses survive in non-air moisture environments?

On the Internet there are plenty of information that viruses don't live long after they were exposed to air, after they starting to dry out. But it's hard to find an information on how long viruses ...
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1answer
41 views

Can ACE2 receptors be syntesized? [duplicate]

I read that there are labs that can produces the spikes of the coronavirus. I wonder can they also synthesize ACE2 receptors or parts of them? If yes, can they be used as drugs?
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Do person with strong immune system have less chance of surviving SARS-COV-2 attack?

In most of the cases dealing with SARS-COV-2 disease, the major mortality cause is due to cytokine storm in response to Corona-virus that also attack healthy organs causing multiple organ failure. ...
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2answers
12k views

Are the social-distancing measures implemented against SARS-CoV-2 also suppressing the spread of other viruses?

With social-distancing measures being implemented in many countries I would expect other viruses, like the ones that cause seasonal flus, to have also a hard time propagating in these circumstances. ...
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2answers
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VPg priming of the replication of RNA viruses

I'm doing a presentation on the replication of SARS-CoV-2 for my chemistry class, and I found that to replicate its RNA, the virus uses RNA-dependent RNA polymerase, which is primed by a VPg primer. ...
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Understand and reproduce withdrawn publication method - Blastp - covid19

I try to reproduce the method of this withdrawn paper. I know this paper has been debunked and withdrawn. I am curious to understand the details of the method used on it. I am a programmer and I don't ...
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1answer
109 views

Factors of infection rate

I refer to J.H. Jones' Notes on R0. Preliminaries The standard SIR model consists of a system of three differential equations $$ds/dt = -\beta s i$$ $$di/dt = \beta s i - \nu i$$ $$dr/dt = \nu i$...
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Does coronavirus survives more on a surface if it's not exposed to air?

Coronavirus survives 72 and 24 hours on hard surfaces (steel, plastic etc) and soft surfaces ( clothes etc) respectively. Does this data change if the surface is not exposed to air? If yes, then by ...
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2answers
40 views

Exact definition of homoplasy?

I am a poor mathematician looking into the Sars-Cov-2 genome. Is there a proper definition of the word homoplasy? Is it just mutations that happened independently or does there have to be indications ...
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2answers
92 views

Genomic location-coordinate of RdRp of SARS-CoV2

I understand that nsp12 is the RdRp protein in the ORF1 of SARS-CoV2 genome. And nsp12 starts from the starting nucleotide base of orf1ab. Could you please tell me the exact genomic location ...
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1answer
102 views

Triangulation number of the SARS CoV-19 virus

Is the triangulation number of the SARS CoV-19 virus capsid, in the sense of the Caspar-Klug theory, known? In case the Caspar-Klug theory does not apply to it, is it known what is its tiling, in ...
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1answer
29 views

What coronaviruses have been identified in racoon dogs?

Christian Dorsten says in an (Apr 26) interview in the Guardian that racoon dogs as [intermediate] source of coronavirues have been overlooked (in China): Q: What do we know about that intermediate ...
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1answer
112 views

Why is ACE2 not used as drug against covid? [closed]

Can ACE2 be produced and used as drug against covid? I read it is the receptor molecule. If it is in the organism the virus should bind to it and could not attack cells anymore? Is that right?
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1answer
658 views

Why are men more susceptible to severe COVID-19?

It seems that globally, men are more susceptible to severe COVID-19 than women: https://www.theguardian.com/world/2020/mar/26/men-are-much-more-likely-to-die-from-coronavirus-but-why This is seen in ...
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Who define the SARS-CoV-2 haplotypes?

If you look in this paper https://www.nejm.org/doi/full/10.1056/NEJMoa2006100 they work with several haplotypes of the virus. They claim that the definitions of the haplotypes come from GISAID/...
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23 views

Does the cell release the empty capsids?

The virus via the spike of the capsid connects to a receptor in a cell, then the DNA enters the cell wall. My question is what happens to the capsid - does it stay connected to the receptor or is ...
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1answer
68 views

Do we know if dogs are asymptomatic transmiters of sars-cov-2?

Dogs do not use mask when going for a walk nor they observe the security distance. On the contrary, they frequently join their noses, and put their noses where other dogs had put them before or had ...
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1answer
85 views

Can/have bacteria been engineered to express ACE 2 receptors?

In light of SARS-COV-2 binding to the ACE 2 protein in human cells, I was wondering if any bacteria exist or could exist that possess this membrane protein. If not, do you believe that an ACE 2 like ...
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1answer
42 views

COVID-19 Infection rate related to population size?

Recently, in the UK's daily government briefing they started showing the graphs that compare national death rates, adjusted by the population size of each country. I understand the various reasons ...
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31 views

Is it possible to force Sars-Cov-2 virus to mutate?

The title may definitely be a stupid question since I have no background in biology. I would like to know if the coronaviruses or any other can be manipulated artificially so that they stop spreading ...
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1answer
39 views

How do biologists infect cells with viruses within a lab setting? [closed]

I'm writing an experimental proposal as my final paper for my single molecule biophysics class. Part of the procedure I wrote involves intentionally infecting a culture of HeLa cells with SARS-CoV-2 ...
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1answer
70 views

Why do COVID19 serology tests focus on the nucleocapsid while vaccine efforts focus on the spike?

When I look at the specification sheets for many of today's serology tests like the new Roche test or the Abbott test, they use a nucleocapsid antigen in the test, looking for anti-nucleocapsid ...