All Questions
Tagged with inheritance or genetics
371 questions with no upvoted or accepted answers
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The village of Twins — Mystery behind and Scope
With the presence of more than 200 twins, Kodinhi , a village situated in Malappuram District in Kerala , India , is popularly known as the "Village of Twins".This phenomenon of large ...
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308
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How to estimate heritability from breeding data
I have a lot of plant-breeding data (tens of thousands of results) that are composed of phenotypes of parents and offspring. The plants however went trough years of selection and it is not balanced. ...
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86
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What are the additional considerations for primer design in ancient DNA?
I'm familiar with the principles of primer design and have previously designed primers for use in modern DNA. However, in my current project I am working with ancient DNA (nuclear gene) and need to ...
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Is there a name for this type of diagram?
Is there any commonly used name for this type of diagram / symbology? I have not been able to find them referred to by any name.
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effect of background selection on promoter regions compared to distant enhancers?
Has anyone looked at the effect of background selection on the levels of conservation of promoter regions compared to distant enhancers? Do promoter regions have a higher conservation due to ...
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4
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84
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ABO allele frequencies: Why use the EM algorithm?
In textbooks and lecture notes and slides posted online, determining allele frequencies using blood type information (ABO), under the assumption of Hardy-Weinberg equilibrium, is accomplished using ...
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4
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97
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Mechanism behind Philadelphia chromosome translocation?
I was reading up on causative factors of leukemia on medicinenet and I came across the following statement:
...an exchange between chromosomes 9 and 22 leads to what is known as the Philadelphia ...
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4
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59
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Number of hair cycles in humans
I've seen several websites claim the amount of hair cycles a follicle will go through is predetermined at around 25-30 complete cycles. Is there any genetic evidence to validate this claim? How can ...
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121
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How many generations apart can a DNA test for blood relations be valid?
Suppose an American suspects he is a descendant of George Washington and he has a strand of hair of George Washington. Can a DNA test be done to prove that he is indeed a true descendant of the great ...
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130
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Isn't heritability more important to genic capture than just genetic variance?
Rowe & Houle (1996) give two criteria for the selection of costly female choice:
Condition dependence of sexually selected traits
High genetic variance in condition
Regarding heritability, ...
- 466
4
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197
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Eye color genetics
I am trying to find a model to link the phenotype eye color to its genotypes.
I know that there exists a simple model from Davenport, which explains {brown,blue} eyes. Further, there is an extended ...
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3
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How to model the relationship between environments based on environmental covariates in a genomic prediction context
I have a dataset with different wheat lines in multiple environments. For each line various traits are measured (e.g. grain yield). I am trying to set up various genomic prediction models (linear ...
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3
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71
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Database of unique attributes of biological model systems
I am interested in deviations from standard eukaryotic biological mechanisms:
Sperm chromatin lacks nucleosomes, and are instead highly condensed by protamines. (most eukaryotic chromatin has ...
- 131
3
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74
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What does "dissection-based microscopy" mean as described here, and how can it give genetic information?
The Phys.org article 'DNA microscopy' offers entirely new way to image cells references the new Open Access paper in Cell DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical ...
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3
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213
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Regulation of LBD33 genes Arabidopsis. If LBD 33 gene is up-regulated by auxin then why does expression decrease when increasing auxin concentration?
I have a question regarding the regulation of lateral boundary domain genes in Arabidopsis (specifically LBD33). I am an undergraduate student trying to understand the results of a lab where I measure ...
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122
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How does the new discovery that mitochondrial dna is inherited from both parents change population genetics and other dates?
This new study seem to have pretty much proven that mtDNA is inherited from both parents. I assume that this would lead to most age estimates of ancient human ...
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3
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58
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Offspring of parents with different number of chromosomes
Many papers report that dog-whelks (Nucella lapillus) show a distinct chromosomal polymorphism between populations of 2n = 24 up to 2n = 36. Could somebody please tell me how many chromosomes the F1 ...
3
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Relationship between inbreeding and sterility in humans
In general, inbred individuals tend to be at increased risk of sterility as shown in cows (Gonzales-Recio, 2007) or in leghorns (Nordskog and Cheng, 1988) for examples. I only have very quickly looked ...
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3
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79
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How are animal patterns encoded in the dna?
After seeing the patterns on the feathers of a argusianus argus pheasant (shown below), I am curious where is the information that encodes a pattern for a particular bird, and what form is this ...
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3
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90
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Why are animal mitochondrial genomes so conserved and small in comparison to those of plants?
Background
Levings and Brown (1989):
Higher plant mitochondrial genomes are much larger and
more complex than those of other organisms. They vary
in size from about 200 kb in Brassica species ...
- 68.3k
3
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26
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Condition for a genetically modified group of cell to remain and to spread?
I was wondering: when a treatment modifies a group of gene (like in gene therapy), what makes a group of cell remains?
I mean, when a cell divide itself to create new ones, if a cell was initially ...
- 205
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167
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Difference between Classic Satellite DNA and Microsatellites/Minisatellites
I am very new to this community and have a basic question about repetitive DNA sequences.
How is different (classic) satellite DNA from microsatellites/minisatellites?
All textbooks give concrete ...
- 143
3
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178
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question about fast/slow muscle twitch fibers
Here are my questions (I have several)
1) Are the fast twitch muscle fibers dominant or recessive as opposed to the slow?
2) Are people of mixed race/greatest genetic diversity in their background, ...
3
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82
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Is Phenylalanine hydroxylase gene biallelic?
Since the PAH gene is biallelic, and there are many disease causing mutations, most PKU patients are compound heterozygotes.
(paper)
Compound heterozygosity in medical genetics is the condition ...
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3
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1k
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Are epicanthic folds a dominant trait?
My state (Tripura) originally had a mostly mongoloid-feature-possessing population (ethnic group: Tripuri). Recently a large number of non-mongoloid people (ethnic group: Bengali) have migrated to ...
user15816
3
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198
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Question about genetic recombination
I am having some difficulty understanding a few things about genetic recombination, in part because of confusion from different diagrams in books.
First of all, I wanted to verify whether I have ...
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3
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77
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Why might the chirality of gastopods be dominantly dextral?
This wikipedia page on gastropods provides a definition of chirality, and briefly describes the genetic mechanisms behind why a shell is wound left (sinistral) or right (dextral) handed. It also ...
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78
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Could trees be engineered to produce rainfall-nucleators?
Scientists are using genetic engineering to make trees produce more terpenes. Is it possible to genetically engineer trees to produce more hygroscopic volatile organic compounds? These trees could be ...
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123
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What is the effective population size of a simple two deme metapopulation?
I am confused as to how to compute the effective population size $N_e$ of a theoretical structured population. Let's consider here a simple case study.
Imagine a 2-deme metapopulation. Each deme is ...
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3
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271
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Population size and genetic drift - What are the evidences?
Wright-Fisher model
From the Wright-Fisher model of genetic drift, the random sampling of allele from one generation to the next is taken from a binomial distribution with parameters $2N$ and $p$, ...
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3
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117
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Is $F_{ST}$ a probability and a correlation coefficient?
$F_{ST}$ is one of the most famous and most important statistics of all of evolutionary biology. Yet, many people misunderstand it or misuse the classical results from the literature on $F_{ST}$ (...
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3
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697
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How should one interpret heritability? Is it related to $R^2$?
From Wikipedia:
Heritability estimates are often misinterpreted if it is not understood that they refer to the proportion of variation between individuals on a trait that is due to genetic factors. ...
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40
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Fur genetics - what are the causes of fur colour decision?
This Australian Shepherd puppy's father is a black-tri; mother is a blue merle. What would cause this dog to have so much white color?
Are there any general explanations as to why this might happen ...
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99
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How do sex biased genes evolve?
I am wondering how do genes become sex-biased? that is, how does a gene evolve expression which is regulated in a sex-specific manner (assuming no effect from sex-limited Y/W chromosomes).
I ...
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3
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70
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Do genetic modifications exist to enhance the taste of tomatoes?
GM tomatoes seem less tasty. Has there been any research on GMOs with regard to taste?
Can scientists introduce a gene to, let's say, tomatoes, which would enhance the flavour? If not, why?
- 428
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107
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Problem involving selfing (inbreeding it with itself) a plant to generate purebred lines
I am working on a past exam problem where the first bit is as follows
A plant is repeatably selfed to generate inbred lines. Let $\mathbb{P}(He|He)$ denote the probability that a heterozygous ...
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3
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213
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Modified Mendelian Ratios Problem
I'm studying modified Mendelian ratios. I've got a theoretical problem that I'm stumped on:
A species of bird may have normal wings, or a mutation that causes frazzled wings.
I do 15 identical ...
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70
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examples of chromosomal aberrations with lack of sexual chromosomes?
Are there any examples in animals where individuals survive having no copies of their sexual chromosomes?
- 1,790
3
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0
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294
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Gibson assembly using NeBuilder
I am supposed to construct a plasmid that contains features from two other plasmids.
My strategy is to generate three fragments form the two other plasmids. I was encouraged to try Gibson assembly, ...
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89
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What are polytene bands, and why are they there?
Drosophila polytene chromosomes have been particularly useful in genetic research, as it made cytogenetic gene mapping possible with very little effort. This was primarily accomplished due to polytene ...
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40
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How to understand restriction mapping a quarter of a century later?
Today, biology is virtually all based on massively parallel sequencing, long-strand sequencing, and metagenomic; looking back at old restriction mapping is not straightforward (at least for me).
For ...
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446
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How pitch of a DNA Helix is 3.4 nm?
How pitch of a DNA Helix is 3.4 nm?
In the image that I have attached, the numbers with prime represent the number of base pair and normal numbers represent the number of gap elements between two base ...
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39
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What portion of the human genome is dedicated to the developement of the fetus?
I was thinking about how we don't know the function of a large portion of DNA and I thought maybe it's because it's only used during the development of the fetus
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101
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How is melatonin production related to proteins produced by clock genes?
I am a high school student learning about feedback mechanisms. My teacher gave an example of how proteins produced by clock genes are related to melatonin production. However, I'm confused about the ...
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190
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If crossing over did not occur, would pairs of cells after meiosis II have the same genes?
If crossing over did not occur, would there be two pairs of cells with the same chromosomes after meiosis II? This question came to my mind while I was reading through my bio textbook. After meiosis I,...
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59
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How are correlations between genes and observed traits made?
If a given organism has a certain characteristic (a chemical that's produced, a place an organ or organelle is in, a particular behavior), what's the general procedure for correlating that ...
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74
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Inferring mother's allele probability based on father and children
I am currently in the process of analyzing our family's genome. I do have access to his, mine and our father's genome, but not to our mother's (deceased). I was wondering how I could combine our 3 ...
2
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144
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How can drone bees be born from unfertilized eggs?
I am learning about Drone bees and I keep reading that they are born from unfertilized eggs.
Now here is my question: if eggs are gametes and therefore reproductive cells, how can they turn into a new ...
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53
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What forms a mutation hotspot?
From https://en.wikipedia.org/wiki/Recombination_hotspot#:~:text=Recombination%20hotspots%20are%20regions%20in,that%20of%20the%20surrounding%20region.
I understand that hotspots may arise when certain ...
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81
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What is the heredity model of the following heredity tree?
I have the following heredity tree:
and I need to decide which heredity model it fits the most, with the least number of assumptions, from the following models:
autosome dominant
autosome recessive
...
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